Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153618 | 0.82 | CDYL (0.39) | SMN1; SMN2HRH3TSHRKDM4ELMNA | |
| SCHEMBL6152947 | 0.80 | PLAAT3 (0.34) | HPGDMEN1KMT2A | |
| SCHEMBL6153271 | 0.80 | PLAAT3 (0.34) | HPGDMEN1KMT2A | |
| SCHEMBL6161533 | 0.79 | PLAAT3 (0.37) | HPGDSMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL6161539 | 0.79 | PLAAT3 (0.37) | HPGDSMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL6153048 | 0.79 | HPGD (0.34) | HPGD | |
| SCHEMBL6153049 | 0.79 | HPGD (0.34) | HPGD | |
| SCHEMBL6152351 | 0.77 | L3MBTL1 (0.41) | HPGDSMN1; SMN2HRH3L3MBTL1KDM4E | |
| SCHEMBL6153056 | 0.76 | BACE1 (0.40) | HPGDTSHRMEN1KMT2ALMNA | |
| SCHEMBL6153057 | 0.76 | BACE1 (0.40) | HPGDTSHRMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307449-B1 | 1,4-DIHYDROPYRIDINES AS BRADYKININ ANTAGONISTS | PFIZER PHARMA (JP) | 2005-12-07 | — | — | EP | disclosed |