SCHEMBL61525

SCHEMBL61525

CC1=C(C)c2ccccc2[CH]1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.39
KMT2A Q03164 6/20 0.39
LMNA P02545 4/20 0.39
MAPT P10636 4/20 0.39
ALDH1A1 P00352 3/20 0.39
ACHE P22303 2/20 0.39
KDM4E B2RXH2 2/20 0.39
BCHE P06276 2/20 0.39
POLB P06746 2/20 0.39
PTPRC P08575 2/20 0.39
THRB P10828 2/20 0.39
PKM P14618 2/20 0.39
IDO1 P14902 2/20 0.39
HPGD P15428 2/20 0.39
CES1 P23141 2/20 0.39
RECQL P46063 2/20 0.39
ALOX15 P16050 1/20 0.39
PTPN1 P18031 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PTPN22 Q9Y2R2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218144 0.77 MAP2K7 (0.33) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL217321 0.73 NR1H2 (0.33) CDC25BCDC25AS100A4
SCHEMBL4622303 0.73 MEN1 (0.35) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL2072766 0.73 CDC25A (0.48) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL5078338 0.73 MEN1 (0.35) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL4823700 0.72 L3MBTL1 (0.44) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL5600529 0.72 PDCD1 (0.39) LMNAALDH1A1KDM4EHPGDHSD17B10
SCHEMBL5688926 0.72 CDC25B (0.43) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL216368 0.72 ALDH1A1 (0.38) LMNAALDH1A1ACHEPOLBHPGD
SCHEMBL5611715 0.72 MEN1 (0.34) MEN1KMT2ALMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114716585-B Catalyst system containing aryloxy side-arm metallocene fourth subgroup metal complex and application thereof 吉林大学 2023-02-28 CN claimed
CN-113185545-B Benzylamino-containing side arm Shan Maodi quaternary metal complex and application thereof 吉林大学 2022-11-29 CN claimed
CN-114716585-A Catalyst system containing aryloxy side-arm metallocene fourth subgroup metal complex and application thereof 吉林大学 2022-07-08 CN claimed
CN-111729688-B Application of single cyclopentadienyl fourth subgroup metal complex containing neutral coordination side group 吉林大学 2021-08-17 CN claimed
CN-113185545-A Benzyl amino side arm-containing half-metallocene fourth subgroup metal complex and application thereof 吉林大学 2021-07-30 CN claimed
CN-111662338-B Monocyclopentadienyl fourth subgroup metal complex containing neutral amine or phosphine ligand side group and its use 吉林大学 2021-06-22 CN claimed
CN-108250340-B Metallocene catalyst system and method for catalyzing olefin polymerization by using same 北京引发科技有限公司 2021-03-19 CN claimed
CN-108250341-B Catalyst system containing metallocene compound and method for catalyzing olefin polymerization by using catalyst system 北京引发科技有限公司 2020-12-11 CN claimed
CN-111729688-A Application of single cyclopentadienyl fourth subgroup metal complex containing neutral coordination side group 吉林大学 2020-10-02 CN claimed
CN-111662338-A Monocyclopentadienyl fourth subgroup metal complex containing neutral amine or phosphine ligand side group and its use 吉林大学 2020-09-15 CN claimed
US-6140521-A CONTACTING A CHARGE-NEUTRAL GROUP IV METAL COORDINATION COMPLEX HAVING AT LEAST TWO LEWIS BASIC GROUPS WITH A CHARGE-NEUTRAL ALUMINUM COORDINATION COMPLEXES HAVING LEWIS ACIDIC ALUMINUM ATOMS; OLEFIN POLYMERIZATION CATALYST THE DOW CHEMICAL COMPANY (US) 2000-10-31 US claimed
WO-2000009523-A1 ANSA-GROUP-4-METAL BIS (.MU.-SUBSTITUTED) ALUMINUM COMPLEXES THE DOW CHEMICAL COMPANY (US) 2000-02-24 WO claimed
WO-2000009524-A1 ANSA GROUP-4- METAL BIS (.MU.-SUBSTITUTED) ALUMINUM METALLOCENES THE DOW CHEMICAL COMPANY (US) 2000-02-24 WO claimed
EP-0948547-A1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION THEREOF Montell Technology Company bv (NL) 1999-10-13 EP claimed
EP-0918757-A1 8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS GEORGETOWN UNIVERSITY (US) 1999-06-02 EP claimed
CN-1216548-A Yttrium-containing metal complexes and olefin polymerization process DOW CHEMICAL CO (US) 1999-05-12 CN claimed
WO-1999021896-A1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION THEREOF MONTELL TECHNOLOGY COMPANY BV (NL) 1999-05-06 WO claimed
EP-0901497-A1 YTTRIUM CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1999-03-17 EP claimed
WO-1997043268-A1 8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS GEORGETOWN UNIVERSITY (US) 1997-11-20 WO claimed
WO-1997043294-A1 YTTRIUM CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1997-11-20 WO claimed