Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2875257 | 0.84 | SIGMAR1 (0.47) | L3MBTL1SLC6A3MAPTMAPK1NPSR1 | |
| SCHEMBL10413132 | 0.82 | SIGMAR1 (0.43) | L3MBTL1SLC6A4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9697226 | 0.82 | MAPT (0.49) | L3MBTL1SLC6A3MAPTMAPK1NPSR1 | |
| SCHEMBL10696607 | 0.82 | L3MBTL1 (0.49) | L3MBTL1SLC6A3MAPTMAPK1NPSR1 | |
| SCHEMBL30463655 | 0.80 | DPP7 (0.33) | L3MBTL1DPP7SLC6A3MAPTMAPK1 | |
| SCHEMBL18939311 | 0.79 | SLC6A3 (0.54) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11180712 | 0.79 | L3MBTL1 (0.46) | L3MBTL1SLC6A3MAPTMAPK1NPSR1 | |
| SCHEMBL9697384 | 0.78 | L3MBTL1 (0.46) | L3MBTL1DPP7SLC6A3MAPTMAPK1 | |
| SCHEMBL18289737 | 0.77 | MAPK1 (0.40) | L3MBTL1SLC6A3MAPTMAPK1NPSR1 | |
| SCHEMBL23959715 | 0.77 | SLC6A3 (0.55) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124552-A4 | ANTITUMOR CHRYSENE DERIVATIVES | REGENTS BOARD OF (US) | 2005-01-05 | — | — | EP | disclosed |
| EP-1124552-A1 | ANTITUMOR CHRYSENE DERIVATIVES | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000024394-A1 | ANTITUMOR CHRYSENE DERIVATIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-05-04 | — | — | WO | disclosed |