Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152761 | 0.81 | NOS3 (0.43) | NOS3NOS1NOS2 | |
| SCHEMBL5833799 | 0.81 | NOS3 (0.40) | NOS3NOS1NOS2 | |
| SCHEMBL6153072 | 0.80 | NOS3 (0.42) | NOS3NOS1NOS2 | |
| SCHEMBL6152640 | 0.80 | NOS3 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL6152394 | 0.78 | NOS3 (0.41) | NOS3NOS1NOS2 | |
| SCHEMBL6153153 | 0.78 | NOS1 (0.67) | NOS3NOS1NOS2 | |
| SCHEMBL6583121 | 0.67 | NOS3 (0.44) | NOS3NOS1NOS2 | |
| SCHEMBL6620000 | 0.66 | RPS6KA2 (0.35) | NOS1 | |
| SCHEMBL5833517 | 0.64 | NOS3 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL5833347 | 0.64 | NOS3 (0.38) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084109-B1 | 2-AMINOPYRIDINES CONTAINING FUSED RING SUBSTITUENTS AS NITRIC OXIDE SYNTHASE INHIBITORS | PFIZER PROD INC (US) | 2005-01-26 | — | — | EP | disclosed |