Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 19/20 | 0.67 |
| ▸ | NOS3 | P29474 | 16/20 | 0.67 |
| ▸ | NOS2 | P35228 | 13/20 | 0.67 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5838088 | 0.80 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL6152653 | 0.78 | NOS3 (0.42) | NOS1NOS3NOS2 | |
| Dimethylamine SCHEMBL6153154 | 0.77 | NOS1 (0.69) | NOS1NOS3NOS2 | |
| SCHEMBL5833670 | 0.76 | NOS1 (0.65) | NOS1NOS3NOS2 | |
| SCHEMBL6153197 | 0.75 | NOS1 (0.50) | NOS1NOS3NOS2IDH1 | |
| SCHEMBL6152558 | 0.75 | NOS1 (0.91) | NOS1NOS3NOS2 | |
| SCHEMBL6153070 | 0.74 | NOS1 (0.75) | NOS1NOS3NOS2 | |
| SCHEMBL5833985 | 0.73 | NOS3 (0.69) | NOS1NOS3NOS2 | |
| SCHEMBL6152435 | 0.72 | NOS3 (0.69) | NOS1NOS3NOS2 | |
| SCHEMBL6153424 | 0.69 | NOS1 (0.50) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084109-B1 | 2-AMINOPYRIDINES CONTAINING FUSED RING SUBSTITUENTS AS NITRIC OXIDE SYNTHASE INHIBITORS | PFIZER PROD INC (US) | 2005-01-26 | — | — | EP | disclosed |