Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.65 |
| ▸ | CES1 | P23141 | 1/20 | 0.65 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28710457 | 0.84 | CES2 (0.62) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL21804751 | 0.84 | CES2 (0.62) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL1383788 | 0.84 | PARP1 (0.69) | CES2CES1PARP1NPC1RAB9A | |
| Formaldehyde SCHEMBL11142552 | 0.81 | CES2 (0.69) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL2682408 | 0.81 | CES2 (0.81) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL6827745 | 0.81 | CES2 (0.74) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL63427 | 0.81 | CES2 (0.74) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL29351426 | 0.81 | CES2 (0.74) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL25756754 | 0.81 | CES2 (0.62) | CES2CES1PARP1NPC1RAB9A | |
| SCHEMBL20548698 | 0.81 | RXRA (0.47) | CES2CES1NPC1RAB9AABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118266572-A | Application of 3-methoxyphenyl-2-acrylic compound as bitter taste inhibitor | 华南理工大学 | 2024-07-02 | — | — | CN | claimed |
| CN-118266572-A | Application of 3-methoxyphenyl-2-acrylic compound as bitter taste inhibitor | 华南理工大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-109651253-B | Phenylpropanoid ester derivative and application thereof as neuroprotective medicament | 上海医药工业研究院 | 2022-03-25 | — | — | CN | disclosed |
| WO-2021129082-A1 | METHOD FOR SYNTHESIZING α-ACRYLIC ACID COMPOUND BY USING PALLADIUM TO CATALYZE CARBON DIOXIDE AND ALKYNE | 华南理工大学 | 2021-07-01 | — | — | WO | disclosed |
| CN-109369637-B | Novel kojic acid derivative containing 1,3, 4-thiadiazole and application thereof | 湖南科技大学 | 2021-04-06 | — | — | CN | disclosed |
| CN-110156649-A | A kind of method that silver catalysis prepares 3- phenyl -2- phenyl disulphanes Tri- n -butyltin methacrylate compound | 浙江农林大学暨阳学院 | 2019-08-23 | — | — | CN | disclosed |
| CN-104744189-A | Method for preparing alpha-aryl acrylic acid by carbon dioxide | UNIV CHANGZHOU | 2015-07-01 | — | — | CN | disclosed |
| EP-1233964-B1 | NEW USE AND NOVEL N-AZABICYCLO-AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-06-22 | — | — | EP | disclosed |
| US-6683090-B1 | N-(1-AZABICYCLO(2.2.2)OCT-3-YL)PROPENAMIDE DERIVATIVES; PSYCHOTIC AND INTELLECTUAL IMPAIRMENT DISORDERS | ASTRAZENECA AB (SE) | 2004-01-27 | — | — | US | disclosed |
| US-6465485-B1 | SUCH AS 7-CYANO-2-(2-(1-(4-(2-INDOLYL)CARBOXAMIDO)CYCLO-HEXYL)ETHYL)-1,2,3,4 -TETRAHYDROISOQUINOLINE; ANTIPSYCHOTIC AGENTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-10-15 | — | — | US | disclosed |
| EP-1233964-A1 | NEW USE AND NOVEL N-AZABICYCLO-AMIDE DERIVATIVES | AstraZeneca AB (SE) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001036417-A1 | NEW USE AND NOVEL N-AZABICYCLO-AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-05-25 | — | — | WO | disclosed |