Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 7/20 | 1.00 |
| ▸ | CASP6 | P55212 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 12/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152043 | 1.00 | GFER (1.00) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL188503 | 1.00 | GFER (1.00) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL3548441 | 0.93 | GFER (0.87) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL23126615 | 0.85 | CASP6 (0.73) | GFERCASP6KMT2AMEN1ALDH1A1 | |
| SCHEMBL28806386 | 0.85 | GFER (0.73) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL11936072 | 0.83 | MAPT (0.79) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL854196 | 0.83 | GFER (0.71) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL1128293 | 0.83 | GFER (0.71) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL82046 | 0.83 | GFER (0.71) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL5725441 | 0.83 | GFER (0.71) | GFERCASP6MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050120494-A1 | Triazacyclononane derivatives substituted on at least one of the nitrogen atoms with a substituted or unsubstituted 4'-aminophenyl group, for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-06-09 | — | — | US | claimed |
| EP-1518860-A1 | Triazacyclononane derivatives substituted on at least one of the nitrogene atoms by a 4-aminophenyle group for dyeing keratinic fibres | L'OREAL (FR) | 2005-03-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050120494-A1 | Triazacyclononane derivatives substituted on at least one of the nitrogen atoms with a substituted or unsubstituted 4'-aminophenyl group, for dyeing keratin fibres | KRT18, TUBB6, TUBB1 | GFER 1599/4885CASP6 1541/4885MAPT 945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.