Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 7/20 | 1.00 |
| ▸ | CASP6 | P55212 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 12/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152043 | 1.00 | GFER (1.00) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL6152986 | 1.00 | GFER (1.00) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL3548441 | 0.93 | GFER (0.87) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL23126615 | 0.85 | CASP6 (0.73) | GFERCASP6KMT2AMEN1ALDH1A1 | |
| SCHEMBL28806386 | 0.85 | GFER (0.73) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL11936072 | 0.83 | MAPT (0.79) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL854196 | 0.83 | GFER (0.71) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL1128293 | 0.83 | GFER (0.71) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL82046 | 0.83 | GFER (0.71) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL5725441 | 0.83 | GFER (0.71) | GFERCASP6MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108931-B | Tofenamic acid derivative and preparation and application thereof | 南华大学附属第一医院 | 2024-06-14 | — | — | CN | claimed |
| US-20050182050-A1 | Therapeutic heterocyclic compounds | ASTRAZENECA AB (SE) | 2005-08-18 | — | — | US | claimed |
| US-6812225-B2 | PYSCHOLOGICAL DISORDERS; ANTIDEPRESSANTS | ASTRAZENECA AB (SE) | 2004-11-02 | — | — | US | claimed |
| CN-1131222-C | Benzamide derivatives and their use as inhibitors of APOB-100 secretion | GLAXO GROUP LTD (GB) | 2003-12-17 | — | — | CN | claimed |
| WO-2003047575-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | claimed |
| US-20030013708-A1 | Therapeutic heterocyclic compounds | ASTRAZENECA AB (SE) | 2003-01-16 | — | — | US | claimed |
| CN-1334808-A | Benzamide derivatives and their use as inhibitors of APOB-100 secretion | GLAXO GROUP LTD (GB) | 2002-02-06 | — | — | CN | claimed |
| EP-1135378-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS APOB-100 SECRETION INHIBITORS | GLAXO GROUP LIMITED (GB) | 2001-09-26 | — | — | EP | claimed |
| WO-2000032582-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS APOB-100 SECRETION INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-06-08 | — | — | WO | claimed |
| US-12466812-B2 | Pyridinyltriazine derivative having protein kinase inhibitory activity, and pharmaceutical composition for preventing, ameliorating, or treating cancer comprising same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2025-11-11 | — | — | US | disclosed |
| US-20250282736-A1 | SMALL MOLECULE MODULATORS OF HUMAN PREGNANE X RECEPTOR | ST JUDE CHILDRENS RES HOSPITAL (US) | 2025-09-11 | — | — | US | disclosed |
| US-20250214945-A1 | THIOBENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2025-07-03 | — | — | US | disclosed |
| CN-119431239-A | Compounds, pharmaceutical compositions, kits and uses thereof | 密执安大学评议会 | 2025-02-14 | — | — | CN | disclosed |
| EP-4506346-A1 | THIOBENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF | Korea University Research and Business Foundation (KR) | 2025-02-12 | — | — | EP | disclosed |
| EP-0321131-A2 | Triazole antifungal agents | Pfizer Limited (GB) | 1989-06-21 | — | — | EP | disclosed |
| US-4797401-A | 4-Substituted-1-(4-alkylsulphonamidophenyl)piperazines as antiarrhythmic agents | PFIZER INC. (US) | 1989-01-10 | — | — | US | disclosed |
| US-4788196-A | Phenyl piperazine anti-arrhythmia agents | PFIZER INC. (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0257864-A1 | Antiarrhythmic agents | Pfizer Limited (GB) | 1988-03-02 | — | — | EP | disclosed |
| EP-0244115-A2 | Phenyl-piperazine anti-arrhythmia agents | Pfizer Limited (GB) | 1987-11-04 | — | — | EP | disclosed |
| US-4698352-A | 4-oxo-1,4-dihydronicotinic acid derivatives, salts thereof, and antibacterial agents containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182050-A1 | Therapeutic heterocyclic compounds | HTR1B, HTR1D, HTR1A | GFER 4013/4885CASP6 2877/4885MAPT 653/4885 |
| US-20030013708-A1 | Therapeutic heterocyclic compounds | HTR1A, HTR1D, HTR1B | GFER 4158/4885CASP6 2951/4885MAPT 661/4885 |
| US-12466812-B2 | Pyridinyltriazine derivative having protein kinase inhibitory activity, and pharmaceutical composition for preventing, ameliorating, or treating cancer comprising same | FGFR3, FGFR1, FGFR4 | GFER 4059/4885CASP6 3995/4885MAPT 2488/4885 |
| US-20250214945-A1 | THIOBENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF | TTBK2, TUBB3, TUBB | GFER 4541/4885CASP6 543/4885MAPT 157/4885 |
| US-20250282736-A1 | SMALL MOLECULE MODULATORS OF HUMAN PREGNANE X RECEPTOR | NR1H4, NR1I2, NR1I3 | GFER 2584/4885CASP6 1160/4885MAPT 3783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.