SCHEMBL6153115

SCHEMBL6153115

CON=C(C(=O)OCOc1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 6/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
MAPT P10636 4/20 0.41
RAB9A P51151 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALOX15 P16050 1/20 0.39
NPC1 O15118 2/20 0.38
PKM P14618 1/20 0.38
LMNA P02545 2/20 0.38
THRB P10828 1/20 0.38
HPGD P15428 1/20 0.38
FFAR1 O14842 1/20 0.37
PARP10 Q53GL7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6152731 0.87 MRGPRX4 (0.43) HIF1ASMN1; SMN2MAPTL3MBTL1TDP1
SCHEMBL8018548 0.81 SMN1; SMN2 (0.61) SMN1; SMN2MAPTRAB9ATDP1NPC1
SCHEMBL6152764 0.81 SMN1; SMN2 (0.61) SMN1; SMN2MAPTRAB9ATDP1NPC1
SCHEMBL28180684 0.81 SMN1; SMN2 (0.47) HIF1ASMN1; SMN2MAPTTDP1LMNA
SCHEMBL8527412 0.81 SMN1; SMN2 (0.34) HIF1ASMN1; SMN2MAPTRAB9AL3MBTL1
SCHEMBL27447670 0.80 ELANE (0.45) HIF1AMAPTRAB9AL3MBTL1TDP1
SCHEMBL7457347 0.77 TSHR (0.50) HIF1ASMN1; SMN2MAPTRAB9AL3MBTL1
SCHEMBL27446293 0.77 TSHR (0.50) HIF1ASMN1; SMN2MAPTRAB9AL3MBTL1
SCHEMBL29140273 0.77 ALOX15 (0.56) SMN1; SMN2RAB9AL3MBTL1TDP1ALOX15
Benzene SCHEMBL7593686 0.77 ALOX15 (0.56) SMN1; SMN2RAB9AL3MBTL1TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP disclosed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO disclosed