SCHEMBL6153186

SCHEMBL6153186

CCC(NC(C)C#N)N(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11050723 0.75
SCHEMBL181414 0.74 PRMT3 (0.33)
SCHEMBL11197514 0.73
SCHEMBL4870362 0.73 TSHR (0.33)
SCHEMBL11237888 0.72 TSHR (0.31)
SCHEMBL28074882 0.72 TDP1 (0.39)
SCHEMBL9775699 0.71 TSHR (0.32)
SCHEMBL21623634 0.69
SCHEMBL3377896 0.69 TSHR (0.38)
SCHEMBL18553317 0.67 LMNA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107922579-A Reactive amine catalysts for polyurethane application 赢创德固赛有限公司 2018-04-17 CN claimed
EP-1207149-B1 Process for the hydrogenation of nitriles on Raney catalysts BASF AG (DE) 2005-01-26 EP claimed
EP-1209146-B1 Process for the hydrogenation of nitriles to primary amines using Raney-catalysts BASF AG (DE) 2004-06-30 EP claimed
US-6677486-B2 HYDROGENATING NITRITES TO PRIMARY AMINES OVER AN ACTIVATED, ALPHA-ALUMINUM OXIDE(AL2O3)-CONTAINING, MACROPOROUS RANEY CATALYST BASED ON AN ALLOY OF ALUMINUM AND AT LEAST ONE TRANSITION METAL BASF AKTIENGESELLSCHAFT (DE) 2004-01-13 US claimed
US-6469211-B2 CONTINUOUS HYDROGENATION OF NITRITES TO PRIMARY AMINES IN THE LIQUID PHASE OVER A SUSPENDED, ACTIVATED RANEY CATALYST BASED ON AN ALLOY OF ALUMINUM AND AT LEAST ONE TRANSITION METAL, IN ABSENCE OF AMMONIA BASF AKTIENGESELLSCHAFT (DE) 2002-10-22 US claimed
US-20020058841-A1 Hydrogenation of nitriles over Raney catalysts BASF AKTIENGESELLSCHAFT (DE) 2002-05-16 US claimed
US-20020058842-A1 Hydrogenation of nitriles over raney catalysts BASF AKTIENGESELLSCHAFT (DE) 2002-05-16 US claimed
US-4482743-A (((DIALKYLAMINO)ALKYL)AMINO)ALKANONITRILE, BIS (( DIALKYLAMINO)ALKL)AMINE, ALKYLENE OXIDE TEXACO INC. (US) 1984-11-13 US claimed
CN-107922579-A Reactive amine catalysts for polyurethane application 赢创德固赛有限公司 2018-04-17 CN disclosed
US-6469211-B2 CONTINUOUS HYDROGENATION OF NITRITES TO PRIMARY AMINES IN THE LIQUID PHASE OVER A SUSPENDED, ACTIVATED RANEY CATALYST BASED ON AN ALLOY OF ALUMINUM AND AT LEAST ONE TRANSITION METAL, IN ABSENCE OF AMMONIA BASF AKTIENGESELLSCHAFT (DE) 2002-10-22 US disclosed
US-20020058842-A1 Hydrogenation of nitriles over raney catalysts BASF AKTIENGESELLSCHAFT (DE) 2002-05-16 US disclosed
US-4482743-A (((DIALKYLAMINO)ALKYL)AMINO)ALKANONITRILE, BIS (( DIALKYLAMINO)ALKL)AMINE, ALKYLENE OXIDE TEXACO INC. (US) 1984-11-13 US disclosed