Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | FRK | P42685 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | NEK4 | P51957 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11173936 | 0.85 | OPRL1 (0.60) | SLC6A2SLC6A4SLC6A3OPRM1OPRL1 | |
| SCHEMBL11173935 | 0.85 | OPRL1 (0.60) | SLC6A2SLC6A4SLC6A3OPRM1OPRL1 | |
| SCHEMBL17222222 | 0.81 | HDAC4 (0.50) | SLC6A2SLC6A3OPRM1HDAC4CCR2 | |
| SCHEMBL17222220 | 0.81 | HDAC4 (0.50) | SLC6A2SLC6A3OPRM1HDAC4CCR2 | |
| SCHEMBL1561226 | 0.77 | HDAC4 (0.59) | OPRM1OPRL1HDAC4CCR2OPRD1 | |
| SCHEMBL7156275 | 0.75 | OPRM1 (0.47) | SLC6A2SLC6A4SLC6A3OPRM1OPRL1 | |
| SCHEMBL7822328 | 0.74 | HDAC4 (0.69) | HDAC4CCR2MEN1KMT2ACYP2C9 | |
| SCHEMBL8110741 | 0.74 | HDAC4 (0.65) | OPRM1OPRL1HDAC4CCR2OPRD1 | |
| Hydrochloric Acid SCHEMBL8106513 | 0.73 | OPRL1 (0.51) | SLC6A2SLC6A4SLC6A3OPRM1OPRL1 | |
| SCHEMBL7464514 | 0.71 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050165057-A1 | Novel piperidine derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-07-28 | — | — | US | disclosed |
| EP-1500648-A1 | NOVEL PIPERIDINE DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
| EP-1337532-A2 | COMPOUND FOR CHELATING A METAL, RADIOPHARMACEUTICAL, MANUFACTURING PROCESS THEREFOR, AND DIAGNOSTIC KIT | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002044175-A2 | COMPOUND FOR CHELATING A METAL, RADIOPHARMACEUTICAL, MANUFACTURING PROCESS THEREFOR, AND DIAGNOSTIC KIT | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165057-A1 | Novel piperidine derivative | ACAT2, ACAT1, LCAT | SLC6A2 3601/4885SLC6A4 2191/4885SLC6A3 3783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.