Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154407 | 0.95 | ALDH1A1 (0.72) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL6154040 | 0.91 | BTK (0.56) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL18361380 | 0.89 | ALDH1A1 (0.69) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL17832684 | 0.84 | ALDH1A1 (0.73) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL10210061 | 0.84 | ALDH1A1 (0.79) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL23742310 | 0.84 | ALDH1A1 (0.66) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL13344251 | 0.84 | ALDH1A1 (0.66) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL4243494 | 0.83 | ALDH1A1 (0.76) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL6154671 | 0.83 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL6154787 | 0.82 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | ALDH1A1 2454/4885NPC1 116/4885RAB9A 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.