Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
| ▸ | PRKX | P51817 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31648185 | 0.87 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL344690 | 0.87 | SLC6A2 (0.48) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| Hydrochloric Acid SCHEMBL31648401 | 0.86 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL1779366 | 0.79 | SLC6A4 (0.78) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL11564867 | 0.79 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL652674 | 0.79 | SLC6A4 (0.78) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL1430298 | 0.79 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL7957756 | 0.79 | SLC6A4 (0.78) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL9390631 | 0.78 | TAAR1 (0.52) | SLC6A2TAAR1MEN1KMT2A | |
| SCHEMBL13207585 | 0.78 | TRPA1 (0.38) | SLC6A4SLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1154989-B1 | VANILLOID ANALOGUES CONTAINING RESINIFERATOXIN PHARMACOPHORES AS POTENT VANILLOID RECEPTOR AGONISTS AND ANALGESICS, COMPOSITIONS AND USES THEREOF | PACIFIC CORP (KR) | 2005-12-14 | — | — | EP | disclosed |
| EP-0916654-B1 | SULFONIC ESTER DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USE THEREOF | KANEKA CORP (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6476076-B1 | Vanilloid analogues containing resinferatoxin pharmacophores as potent vanilloid receptor agonists and analgesics, compositions and uses thereof | PACIFIC CORPORATION (KR) | 2002-11-05 | — | — | US | disclosed |
| US-6410773-B1 | OPTICAL ACTIVE MATERIAL; ENKEPHALINASE INHIBITORS; HYPOTENSIVE AGENTS | KANEKA CORPORATION (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6121477-A | Sulfonic ester derivatives, process for preparing the same, and use thereof | KANEKA CORPORATION (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0461958-B1 | 2-(aminoalkyl)-5-(arylalkyl)1,3-dioxanderivatives their production and their use in therapeutics | SYNTHELABO (FR) | 1994-09-14 | — | — | EP | disclosed |
| US-5192797-A | Antiepileptic and anticonvulsant agents | SYNTHELABO (FR) | 1993-03-09 | — | — | US | disclosed |
| EP-0461958-A1 | 2-(aminoalkyl)-5-(arylalkyl)1,3-dioxanderivatives their production and their use in therapeutics | SYNTHELABO (FR) | 1991-12-18 | — | — | EP | disclosed |