Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | MMP13 | P45452 | 4/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154779 | 0.87 | FAAH (0.45) | FAAHEPHX2LMNA | |
| SCHEMBL6155218 | 0.86 | FAAH (0.56) | FAAHLMNAGAA | |
| SCHEMBL6154733 | 0.85 | EPHX2 (0.57) | FAAHEPHX2 | |
| SCHEMBL6155149 | 0.83 | LMNA (0.52) | FAAHALDH1A1EPHX2LMNAGAA | |
| SCHEMBL10812443 | 0.79 | NPC1 (0.55) | EPHX2LMNA | |
| SCHEMBL16696334 | 0.78 | FAAH (0.56) | CNR1CNR2FAAHALDH1A1PKM | |
| SCHEMBL27798933 | 0.78 | NPC1 (0.57) | CNR1CNR2MMP9MMP13ADAM17 | |
| SCHEMBL23124392 | 0.77 | CHRM2 (0.52) | CNR1 | |
| SCHEMBL30306702 | 0.77 | ANPEP (0.56) | CNR1CNR2ALDH1A1PKMHTT | |
| SCHEMBL12215285 | 0.77 | CNR1 (0.85) | CNR1CNR2ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | claimed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | claimed |
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |