Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155218 | 0.88 | FAAH (0.56) | FAAHSPHK1LMNAHPGDMEN1 | |
| SCHEMBL6154733 | 0.88 | EPHX2 (0.57) | FAAHEPHX2 | |
| SCHEMBL6153869 | 0.87 | CNR1 (0.55) | FAAHLMNAEPHX2 | |
| SCHEMBL6155149 | 0.85 | LMNA (0.52) | FAAHLMNASMN1; SMN2EPHX2 | |
| SCHEMBL10812443 | 0.81 | NPC1 (0.55) | LMNASMN1; SMN2EPHX2NPC1 | |
| SCHEMBL6155721 | 0.79 | EPHX2 (0.46) | EPHX2 | |
| SCHEMBL6157548 | 0.79 | FAAH (0.56) | FAAHLMNAKMT2A | |
| SCHEMBL5696664 | 0.76 | KDM4E (0.59) | FAAHL3MBTL1KMT2AEPHX2 | |
| SCHEMBL29179926 | 0.76 | KDM4E (0.59) | FAAHL3MBTL1KMT2AEPHX2 | |
| SCHEMBL18844824 | 0.76 | CTSK (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | claimed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | claimed |
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |