Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.37 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1841049 | 0.84 | MAPK1 (0.50) | MAPK1ALDH1A1KDM4ETDP1POLB | |
| SCHEMBL6155638 | 0.84 | KMT2A (0.45) | MAPK1ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL334488 | 0.80 | LMNA (0.54) | MAPK1ALDH1A1KDM4ETDP1POLB | |
| SCHEMBL1841148 | 0.80 | RAB9A (0.44) | MAPK1ALDH1A1KDM4ETDP1POLB | |
| SCHEMBL13126455 | 0.77 | MAPK1 (0.46) | MAPK1ALDH1A1KDM4ETDP1POLB | |
| SCHEMBL13126454 | 0.77 | POLB (0.49) | MAPK1ALDH1A1KDM4ETDP1POLB | |
| SCHEMBL7179952 | 0.76 | MAPK1 (0.45) | MAPK1ALDH1A1KDM4ETDP1POLB | |
| SCHEMBL6155240 | 0.76 | MAPK1 (0.45) | MAPK1ALDH1A1KDM4ETDP1POLB | |
| SCHEMBL1841864 | 0.75 | ALDH1A1 (0.44) | MAPK1ALDH1A1KDM4ETDP1POLB | |
| SCHEMBL14343976 | 0.72 | MAPK1 (0.56) | MAPK1ALDH1A1KDM4ETDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580189-A1 | 4-AMINO-5-METHYLPYRAZOLE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Sankyo Agro Company, Limited (JP) | 2005-09-28 | — | — | EP | disclosed |