SCHEMBL6154075

SCHEMBL6154075

BrC1(Br)CC1(Br)Cc1ccccc1.BrC1(Br)CC1(Br)Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.46
MAOB P27338 7/20 0.46
NPSR1 Q6W5P4 2/20 0.41
TRPA1 O75762 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
KDM1A O60341 5/20 0.38
CALM1 P0DP23 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RCOR1 Q9UKL0 1/20 0.36
OPRM1 P35372 1/20 0.35
OPRK1 P41145 1/20 0.35
OPRL1 P41146 1/20 0.35
IDO1 P14902 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2352211 1.00 MAOA (0.46) MAOAMAOBNPSR1TRPA1ALDH1A1
SCHEMBL2347654 0.82 MAOA (0.43) MAOAMAOBNPSR1TRPA1ALDH1A1
SCHEMBL9143534 0.76 MAOA (0.46) MAOAMAOBNPSR1TRPA1ALDH1A1
SCHEMBL29074363 0.70 TSHR (0.44) MAOAMAOBTSHRIDO1
SCHEMBL1170560 0.70 MAOB (0.50) MAOAMAOBTRPA1ALDH1A1TSHR
SCHEMBL28161193 0.68 MAOA (0.48) MAOAMAOBNPSR1KDM1ACALM1
SCHEMBL27812156 0.68 MAOA (0.48) MAOAMAOBTRPA1ALDH1A1TSHR
SCHEMBL27427866 0.68 MAOA (0.48) MAOAMAOBTRPA1ALDH1A1TSHR
SCHEMBL4483495 0.68 MAOA (0.43) MAOAMAOBNPSR1TRPA1ALDH1A1
Hydrochloric Acid SCHEMBL28767976 0.67 MAOA (0.47) MAOAMAOBALDH1A1KDM1AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1409440-A4 A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS ROHM & HAAS (US) 2005-09-14 EP disclosed
EP-1409440-A1 A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS ROHM AND HAAS COMPANY (US) 2004-04-21 EP disclosed
WO-2002068367-A1 A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS ROHM AND HAAS COMPANY (US) 2002-09-06 WO disclosed