Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.43 |
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 6/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352211 | 0.82 | MAOA (0.46) | MAOAMAOBALDH1A1TRPA1TSHR | |
| SCHEMBL6154075 | 0.82 | MAOA (0.46) | MAOAMAOBALDH1A1TRPA1TSHR | |
| SCHEMBL9143534 | 0.73 | MAOA (0.46) | MAOAMAOBALDH1A1TRPA1TSHR | |
| SCHEMBL1170560 | 0.67 | MAOB (0.50) | MAOAMAOBALDH1A1TRPA1TSHR | |
| SCHEMBL28161193 | 0.65 | MAOA (0.48) | MAOAMAOBKDM1ANPSR1CALM1 | |
| SCHEMBL27427866 | 0.65 | MAOA (0.48) | MAOAMAOBALDH1A1TRPA1TSHR | |
| SCHEMBL4483495 | 0.65 | MAOA (0.43) | MAOAMAOBALDH1A1TRPA1TSHR | |
| SCHEMBL27812156 | 0.65 | MAOA (0.48) | MAOAMAOBALDH1A1TRPA1TSHR | |
| Hydrochloric Acid SCHEMBL28767976 | 0.64 | MAOA (0.47) | MAOAMAOBALDH1A1SIGMAR1KDM1A | |
| SCHEMBL2810084 | 0.64 | MAOA (0.52) | MAOAMAOBALDH1A1TRPA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190137-A1 | METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | JACOBSON RICHARD MARTIN | 2011-08-04 | — | — | US | disclosed |
| EP-1409440-A4 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM & HAAS (US) | 2005-09-14 | — | — | EP | disclosed |
| US-20050065033-A1 | Method to inhibit ethylene responses in plants | JACOBSON RICHARD MARTIN (US) | 2005-03-24 | — | — | US | disclosed |
| EP-1409440-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002068367-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065033-A1 | Method to inhibit ethylene responses in plants | ERN1, CTH, CBS | MAOA 1833/4885MAOB 789/4885ALDH1A1 4370/4885 |
| US-20110190137-A1 | METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ERN1, CTH, CBR3 | MAOA 1685/4885MAOB 736/4885ALDH1A1 4363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.