Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.43 |
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | KDM1A | O60341 | 7/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23611125 | 0.70 | MAOA (0.48) | MAOAMAOBKDM1ATRPA1ALDH1A1 | |
| SCHEMBL1546484 | 0.69 | MAOB (0.39) | MAOAMAOBKDM1ALMNAHTT | |
| SCHEMBL5665989 | 0.69 | MAOA (0.39) | MAOAMAOBALDH1A1LMNAOPRM1 | |
| SCHEMBL6154075 | 0.68 | MAOA (0.46) | MAOAMAOBKDM1ARCOR1TRPA1 | |
| SCHEMBL9143534 | 0.68 | MAOA (0.46) | MAOAMAOBKDM1ARCOR1TRPA1 | |
| SCHEMBL2352211 | 0.68 | MAOA (0.46) | MAOAMAOBKDM1ARCOR1TRPA1 | |
| SCHEMBL14779625 | 0.68 | MAOA (0.46) | MAOAMAOBKDM1ARCOR1CALM1 | |
| SCHEMBL1170560 | 0.67 | MAOB (0.50) | MAOAMAOBKDM1ATRPA1ALDH1A1 | |
| SCHEMBL2525239 | 0.67 | MAOA (0.45) | MAOAMAOBKDM1AOPRM1OPRK1 | |
| SCHEMBL5065445 | 0.67 | MAOA (0.45) | MAOAMAOBKDM1AOPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560479-B2 | 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2009-07-14 | — | — | US | disclosed |
| US-20070135508-A1 | 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2007-06-14 | — | — | US | disclosed |
| EP-1615887-A1 | SUBSTITUTED AZABICYCLO HEXANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES, LTD. (IN) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004089899-A1 | SUBSTITUTED AZABICYCLO HEXANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2004-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135508-A1 | 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists | CHRM5, ADRA2B, CHRM4 | MAOA 1113/4885MAOB 140/4885KDM1A 4380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.