SCHEMBL6154131

SCHEMBL6154131

COc1ccc(Nc2cc[c]cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.74
RAB9A P51151 8/20 0.74
GAA P10253 6/20 0.74
MAPK1 P28482 4/20 0.74
NPC1 O15118 4/20 0.74
L3MBTL1 Q9Y468 3/20 0.74
KDM4E B2RXH2 3/20 0.74
TDP1 Q9NUW8 3/20 0.74
THRB P10828 2/20 0.74
RECQL P46063 2/20 0.74
NPSR1 Q6W5P4 1/20 0.74
NR4A1 P22736 1/20 0.61
ALDH1A1 P00352 6/20 0.53
HTT P42858 3/20 0.53
KMT2A Q03164 6/20 0.48
MEN1 O00255 5/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39057 0.86 MAPT (1.00) MAPTRAB9AGAAMAPK1NPC1
SCHEMBL1459772 0.86 MAPT (1.00) MAPTRAB9AGAAMAPK1NPC1
SCHEMBL8943931 0.79 MAPT (0.85) MAPTRAB9AGAAMAPK1NPC1
SCHEMBL7758813 0.79 RAB9A (0.85) MAPTRAB9AGAAMAPK1NPC1
SCHEMBL1921511 0.79 MAPT (0.85) MAPTRAB9AGAAMAPK1NPC1
SCHEMBL12648780 0.79 MAPT (0.85) MAPTRAB9AGAAMAPK1NPC1
SCHEMBL28875309 0.79 MAPT (0.61) MAPTRAB9AGAAMAPK1NPC1
SCHEMBL5541098 0.79 MTNR1B (0.58) MAPTRAB9AGAAMAPK1NPC1
SCHEMBL2370 0.78
Water SCHEMBL27525432 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117534712-A Preparation of I-type iridium complex photosensitizer and application thereof in pharmaceutical field 深圳大学 2024-02-09 CN claimed
EP-1183287-B1 ORGANIC SEMICONDUCTORS BASED ON STATISTICAL COPOLYMERS QINETIQ LTD (GB) 2005-01-26 EP claimed
US-6642332-B1 N-heterocyclic hole and electron transporting groups linked to vinyl group of addition polymers; electronic work function; charge carrier mobility; controlled emmission; storage stability; film-forming; light emitting diode QINETIQ LIMITED (GB) 2003-11-04 US claimed
EP-1183287-A1 ORGANIC SEMICONDUCTORS BASED ON STATISTICAL COPOLYMERS QinetiQ Limited (GB) 2002-03-06 EP claimed
WO-2000069931-A1 ORGANIC SEMICONDUCTORS BASED ON STATISTICAL COPOLYMERS QINETIQ LIMITED (GB) 2000-11-23 WO claimed
CN-117534712-A Preparation of I-type iridium complex photosensitizer and application thereof in pharmaceutical field 深圳大学 2024-02-09 CN disclosed
EP-4276224-A1 FUNCTIONNALISED COPPER ELECTROCHEMICAL CATALYSTS FOR CONVERSION OF CO2 TO SMALL MOLECULES Centre national de la recherche scientifique (FR) 2023-11-15 EP disclosed
CN-114195660-B Optical chromophore compound and composite material containing same 香港城市大学深圳研究院 2023-10-31 CN disclosed
CN-114195660-A Optical chromophore compound and composite material containing same 香港城市大学深圳研究院 2022-03-18 CN disclosed
CN-101490862-B Polymer blends and their use in organic light emitting devices MERCK PATENT GMBH 2013-03-13 CN disclosed
CN-101490862-A Polymer blends and their use in organic light emitting devices MERCK PATENT GMBH (DE) 2009-07-22 CN disclosed
EP-1183287-B1 ORGANIC SEMICONDUCTORS BASED ON STATISTICAL COPOLYMERS QINETIQ LTD (GB) 2005-01-26 EP disclosed
US-6642332-B1 N-heterocyclic hole and electron transporting groups linked to vinyl group of addition polymers; electronic work function; charge carrier mobility; controlled emmission; storage stability; film-forming; light emitting diode QINETIQ LIMITED (GB) 2003-11-04 US disclosed
EP-1183287-A1 ORGANIC SEMICONDUCTORS BASED ON STATISTICAL COPOLYMERS QinetiQ Limited (GB) 2002-03-06 EP disclosed
WO-2000069931-A1 ORGANIC SEMICONDUCTORS BASED ON STATISTICAL COPOLYMERS QINETIQ LIMITED (GB) 2000-11-23 WO disclosed
EP-0832091-A1 C-4' MODIFIED ADENOSINE KINASE INHIBITORS GENSIA, INC. (US) 1998-04-01 EP disclosed
WO-1996040705-A1 C-4' MODIFIED ADENOSINE KINASE INHIBITORS GENSIA SICOR (US) 1996-12-19 WO disclosed