Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ELOVL1 | Q9BW60 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14858192 | 0.96 | MAPT (0.42) | MAPK1MAPTMEN1RAB9AKMT2A | |
| SCHEMBL12090781 | 0.95 | MEN1 (0.44) | MAPK1MAPTMEN1RAB9AKMT2A | |
| SCHEMBL15710231 | 0.92 | MAPK1 (0.44) | MAPK1MAPTMEN1RAB9AKMT2A | |
| SCHEMBL14857706 | 0.84 | BRD4 (0.42) | MAPK1ALDH1A1KDM4EBRD4ELOVL1 | |
| SCHEMBL26404081 | 0.79 | MAPK1 (0.40) | MAPK1ELOVL1 | |
| SCHEMBL25651833 | 0.77 | MAPK1 (0.39) | MAPK1LMNAALDH1A1KDM4EBRD4 | |
| SCHEMBL12881323 | 0.76 | NPBWR1 (0.36) | MAPTMEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL12866738 | 0.75 | NPBWR1 (0.35) | MAPTMEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL13735044 | 0.74 | PKM (0.40) | MAPTMEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL14858423 | 0.74 | PKM (0.40) | MAPTMEN1RAB9AKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| CN-101066950-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2007-11-07 | — | — | CN | disclosed |
| CN-101062918-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2007-10-31 | — | — | CN | disclosed |
| CN-101062917-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2007-10-31 | — | — | CN | disclosed |
| CN-1732155-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2006-02-08 | — | — | CN | disclosed |
| EP-1580189-A1 | 4-AMINO-5-METHYLPYRAZOLE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Sankyo Agro Company, Limited (JP) | 2005-09-28 | — | — | EP | disclosed |