SCHEMBL15710231

SCHEMBL15710231

Cc1ccnn1CC1CC1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.44
MAPT P10636 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
GRM2 Q14416 5/20 0.39
KMT2A Q03164 3/20 0.39
POLB P06746 1/20 0.39
ELOVL1 Q9BW60 1/20 0.36
MEN1 O00255 2/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
NPBWR1 P48145 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14858192 0.92 MAPT (0.42) MAPK1MAPTL3MBTL1ALDH1A1LMNA
SCHEMBL6154196 0.92 MAPK1 (0.42) MAPK1MAPTL3MBTL1ALDH1A1LMNA
SCHEMBL12090781 0.91 MEN1 (0.44) MAPK1MAPTALDH1A1LMNAGRM2
SCHEMBL26404081 0.82 MAPK1 (0.40) MAPK1ELOVL1
SCHEMBL25651833 0.80 MAPK1 (0.39) MAPK1ALDH1A1LMNAELOVL1
SCHEMBL14857706 0.80 BRD4 (0.42) MAPK1ALDH1A1ELOVL1
SCHEMBL16502349 0.77 GRM2 (0.37) MAPTL3MBTL1ALDH1A1LMNAGRM2
SCHEMBL1491074 0.76 KDM4E (0.47) MAPTL3MBTL1ALDH1A1LMNAGRM2
SCHEMBL14838548 0.76 GRM2 (0.46) MAPTL3MBTL1ALDH1A1LMNAGRM2
SCHEMBL26103430 0.76 GRM2 (0.39) MAPTL3MBTL1ALDH1A1LMNAGRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111670186-B Pyrazolopyridine-diamides, their use as pesticides and process for their preparation PI工业有限公司 2023-10-17 CN claimed
WO-2023227696-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed
WO-2023227695-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed
WO-2023217879-A1 PYRROLIDIONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE JANSSEN PHARMACEUTICA NV (BE) 2023-11-16 WO disclosed
CN-111670186-B Pyrazolopyridine-diamides, their use as pesticides and process for their preparation PI工业有限公司 2023-10-17 CN disclosed
US-11771738-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-03 US disclosed
US-11771738-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-03 US disclosed
WO-2023111181-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2023-06-22 WO disclosed
WO-2023107552-A2 PURINES AND METHODS OF THEIR USE Kineta, Inc. (US) 2023-06-15 WO disclosed
US-20230150909-A1 PHENYLACETIC ACID DERIVATIVE, USE THEREFOR, AND PRODUCTION INTERMEDIATE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-05-18 US disclosed
US-20230141212-A1 SUBSTITUTED BENZENECARBOXAMIDES AS IL-17A MODULATORS DICE ALPHA, INC. 2023-05-11 US disclosed
US-11377425-B1 Small molecule modulators of IL-17 LEO PHARMA A/S (DK) 2022-07-05 US disclosed
WO-2022112352-A1 HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2022-06-02 WO disclosed
WO-2021191359-A1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2021-09-30 WO disclosed
WO-2020127685-A1 AMINO-ACID ANILIDES AS SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2020-06-25 WO disclosed
US-9375008-B2 Pyrazole compounds for controlling invertebrate pests BASF SE (DE) 2016-06-28 US disclosed
US-20140142111-A1 Pyrazole Compounds for Controlling Invertebrate Pests BASF SE (DE) 2014-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11377425-B1 Small molecule modulators of IL-17 IL17A, IL15, IL2 MAPK1 1391/4885MAPT 501/4885L3MBTL1 4856/4885
US-20140142111-A1 Pyrazole Compounds for Controlling Invertebrate Pests NOX3, F3, F2 MAPK1 1953/4885MAPT 4224/4885L3MBTL1 188/4885
US-20230141212-A1 SUBSTITUTED BENZENECARBOXAMIDES AS IL-17A MODULATORS IL17A, IL2, IL23R MAPK1 1385/4885MAPT 1639/4885L3MBTL1 4834/4885
US-11771738-B2 Endoparasitic depsipeptides VIP, PREP, VIPR1 MAPK1 2900/4885MAPT 4773/4885L3MBTL1 465/4885
US-20230150909-A1 PHENYLACETIC ACID DERIVATIVE, USE THEREFOR, AND PRODUCTION INTERMEDIATE THEREOF FAR1, NOTUM, ME1 MAPK1 924/4885MAPT 3443/4885L3MBTL1 89/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.