Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155335 | 0.88 | TLR2 (0.52) | CTSKHPGDHSD17B10SMN1; SMN2CYP1A2 | |
| SCHEMBL26555049 | 0.84 | CTSK (0.46) | CTSKHPGDHSD17B10SMN1; SMN2POLB | |
| SCHEMBL26555058 | 0.82 | CTSK (0.46) | CTSKHPGDHSD17B10SMN1; SMN2POLB | |
| SCHEMBL6154861 | 0.81 | TLR2 (0.45) | CTSKHPGDHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL6154733 | 0.81 | EPHX2 (0.57) | CTSK | |
| SCHEMBL26555052 | 0.81 | CTSK (0.45) | CTSKHPGDHSD17B10SMN1; SMN2POLB | |
| SCHEMBL10290433 | 0.79 | HPGD (0.55) | CTSKHPGDHSD17B10SMN1; SMN2POLB | |
| SCHEMBL12206721 | 0.79 | SMN1; SMN2 (0.61) | CTSKHPGDHSD17B10SMN1; SMN2POLB | |
| SCHEMBL12352407 | 0.79 | SMN1; SMN2 (0.64) | CTSKHPGDHSD17B10SMN1; SMN2POLB | |
| SCHEMBL6155149 | 0.79 | LMNA (0.52) | CTSKSMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | claimed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | claimed |
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |