Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154340 | 0.81 | CTSK (0.54) | HPGDHSD17B10CTSKALDH1A1CYP1A2 | |
| SCHEMBL6155335 | 0.79 | TLR2 (0.52) | TLR2HPGDHSD17B10CTSKCYP1A2 | |
| SCHEMBL28770588 | 0.77 | KDM4E (0.47) | CTSKALDH1A1ALOX12RAB9ANPC1 | |
| SCHEMBL355182 | 0.77 | TSHR (0.57) | ALDH1A1CYP1A2TSHRRAB9ANPC1 | |
| SCHEMBL10640793 | 0.77 | TSHR (0.54) | CTSKALDH1A1TSHR | |
| SCHEMBL27448988 | 0.77 | TSHR (0.54) | CTSKALDH1A1TSHR | |
| SCHEMBL10700882 | 0.77 | TSHR (0.54) | CTSKALDH1A1TSHR | |
| SCHEMBL356002 | 0.76 | HSD17B10 (0.56) | HPGDHSD17B10ALDH1A1CYP1A2TSHR | |
| SCHEMBL3783374 | 0.76 | POLB (0.47) | ALDH1A1CYP1A2TSHRRAB9ANPC1 | |
| SCHEMBL19569830 | 0.75 | TSHR (0.55) | CTSKALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | claimed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | claimed |
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |