Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD2 | O60906 | 2/20 | 0.51 |
| ▸ | CHAT | P28329 | 5/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615456 | 1.00 | SMPD2 (0.51) | SMPD2CHATMTNR1AMTNR1BRXRA | |
| SCHEMBL1469842 | 0.85 | TLR8 (0.50) | SMPD2CHATMTNR1AMTNR1BRXRA | |
| SCHEMBL1469843 | 0.85 | TLR8 (0.50) | SMPD2CHATMTNR1AMTNR1BRXRA | |
| SCHEMBL30786727 | 0.83 | ALDH1A1 (0.41) | SMPD2CHATMTNR1AMTNR1BRXRA | |
| SCHEMBL1469100 | 0.83 | ALDH1A1 (0.41) | SMPD2CHATMTNR1AMTNR1BRXRA | |
| SCHEMBL1469098 | 0.83 | ALDH1A1 (0.41) | SMPD2CHATMTNR1AMTNR1BRXRA | |
| SCHEMBL1468842 | 0.82 | CHAT (0.52) | SMPD2CHATMTNR1AMTNR1BRXRA | |
| SCHEMBL1468841 | 0.82 | CHAT (0.52) | SMPD2CHATMTNR1AMTNR1BRXRA | |
| SCHEMBL133603 | 0.81 | CHAT (0.46) | CHATMTNR1AMTNR1BRXRAPTGS1 | |
| SCHEMBL6001652 | 0.81 | CHAT (0.40) | SMPD2CHATMTNR1AMTNR1BRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105714-B2 | Phosphonium salt formation from a phosphine and a carbonium compound, ball milling to form the phosphorus ylide, phosphorylation of an aldehyde or ketone; one pot process; improved catalyst selectivity, efficiency; low temperature, industrial scale | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-09-12 | — | — | US | claimed |
| US-20040260128-A1 | Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2004-12-23 | — | — | US | claimed |
| US-20030176740-A1 | Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2003-09-18 | — | — | US | claimed |
| WO-2003066548-A2 | SOLVENT-FREE MECHANOCHEMICAL PREPARATION OF PHOSPHONIUM SALTS, PHOSPHORUS YLIDES, AND OLEFINS | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2003-08-14 | — | — | WO | claimed |
| EP-3875528-B1 | USE OF A RUBBER COMPOSITION IN A PNEUMATIC TIRE | ZEON CORP (JP) | 2026-01-14 | — | — | EP | disclosed |
| EP-3875528-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME | Zeon Corporation (JP) | 2021-09-08 | — | — | EP | disclosed |
| US-8981152-B2 | Microwave induced single step green synthesis of some novel 2-aryl aldehydes and their analogues | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-03-17 | — | — | US | disclosed |
| US-20140197024-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-07-17 | — | — | US | disclosed |
| US-8779200-B2 | Microwave induced single step green synthesis of some novel 2-aryl aldehydes and their analogues | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-07-15 | — | — | US | disclosed |
| US-20120041234-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGISTRATION OF SOCIETIES ACT (ACT XXI OF 1860)) (IN) | 2012-02-16 | — | — | US | disclosed |
| EP-2202832-B1 | SOLID POLYMER ELECTROLYTE MEMBRANE, METHOD FOR PRODUCING THE SAME, MEMBRANE-ELECTRODE ASSEMBLY FOR FUEL CELL, AND FUEL CELL | SHINETSU CHEMICAL CO (JP) | 2011-11-02 | — | — | EP | disclosed |
| EP-2202832-A1 | SOLID POLYMER ELECTROLYTE MEMBRANE, METHOD FOR PRODUCING THE SAME, MEMBRANE-ELECTRODE ASSEMBLY FOR FUEL CELL, AND FUEL CELL | Shin-Etsu Chemical Co., Ltd. (JP) | 2010-06-30 | — | — | EP | disclosed |
| US-7105714-B2 | Phosphonium salt formation from a phosphine and a carbonium compound, ball milling to form the phosphorus ylide, phosphorylation of an aldehyde or ketone; one pot process; improved catalyst selectivity, efficiency; low temperature, industrial scale | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-09-12 | — | — | US | disclosed |
| US-20040260128-A1 | Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2004-12-23 | — | — | US | disclosed |
| US-6730812-B2 | BALL-MILLING AND SALT FORMATION, CATALYTIC REACTION IN ONE POT; CATALYST SELECTIVITY, EFFICIENCY, LOW TEMPERATURE, SIMPLIFICATION; FORMING UNSATURATED COMPOUNDS, 4-BROMOSTYRENE, ISOPROPENYLNAPHTHALENE/1-/ | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2004-05-04 | — | — | US | disclosed |
| US-20030176740-A1 | Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2003-09-18 | — | — | US | disclosed |
| WO-2003066548-A2 | SOLVENT-FREE MECHANOCHEMICAL PREPARATION OF PHOSPHONIUM SALTS, PHOSPHORUS YLIDES, AND OLEFINS | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040260128-A1 | Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins | CCR4, CCR1, CCR6 | SMPD2 2988/4885CHAT 4484/4885MTNR1A 2257/4885 |
| US-20030176740-A1 | Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins | CCR4, CCR1, CCR6 | SMPD2 2988/4885CHAT 4484/4885MTNR1A 2257/4885 |
| US-20140197024-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | WFS1, EPHX2, MANBA | SMPD2 3915/4885CHAT 3569/4885MTNR1A 3570/4885 |
| US-20120041234-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | AADAC, NAT1, CTRB1 | SMPD2 1821/4885CHAT 849/4885MTNR1A 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.