Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155146 | 0.89 | NPC1 (0.47) | FFAR1ALOX5KMT2ASMN1; SMN2MRGPRX4 | |
| SCHEMBL6886666 | 0.88 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1FFAR1MRGPRX4 | |
| SCHEMBL6155474 | 0.87 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1FFAR1ALOX5NR4A1 | |
| SCHEMBL5968372 | 0.82 | PTGER3 (0.41) | CYSLTR2CYSLTR1FFAR1ALOX5KMT2A | |
| SCHEMBL2785504 | 0.82 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1FFAR1ALOX5KMT2A | |
| SCHEMBL2785501 | 0.82 | VDR (0.49) | CYSLTR2CYSLTR1FFAR1ALOX5 | |
| SCHEMBL6156514 | 0.81 | FFAR1 (0.41) | FFAR1ALOX5NR4A1NR4A2NR4A3 | |
| SCHEMBL6156517 | 0.81 | FFAR1 (0.41) | FFAR1ALOX5NR4A1NR4A2NR4A3 | |
| SCHEMBL6155616 | 0.81 | ALOX5 (0.39) | CYSLTR2CYSLTR1FFAR1ALOX5KMT2A | |
| SCHEMBL6155609 | 0.80 | VDR (0.48) | CYSLTR2CYSLTR1FFAR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |