Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154726 | 0.85 | APP (0.39) | ALOX5PKMMAOBAPPNR4A1 | |
| SCHEMBL6155666 | 0.84 | VDR (0.39) | VDR | |
| SCHEMBL4169944 | 0.82 | VDR (0.50) | VDRALOX5PKMMAOBAPP | |
| SCHEMBL6155566 | 0.81 | VDR (0.48) | VDRALOX5PKMMAOBNR4A2 | |
| SCHEMBL6154549 | 0.78 | VDR (0.49) | VDRALOX5PKMMAOBAPP | |
| SCHEMBL6155992 | 0.76 | VDR (0.62) | VDRALOX5PKMMAOBNR4A1 | |
| SCHEMBL6156005 | 0.76 | VDR (0.62) | VDRALOX5PKMMAOBNR4A1 | |
| SCHEMBL6156380 | 0.74 | VDR (0.50) | VDRALOX5PKMMAOBMRGPRX4 | |
| SCHEMBL6155545 | 0.74 | VDR (0.39) | VDR | |
| SCHEMBL6564829 | 0.73 | VDR (0.50) | VDRALOX5PKMMAOBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | claimed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | claimed |
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |