Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154719 | 0.85 | VDR (0.48) | APPNR4A1NR4A2NR4A3ALOX5 | |
| SCHEMBL4169952 | 0.84 | APP (0.40) | APPNR4A1NR4A2NR4A3ALOX5 | |
| SCHEMBL6155676 | 0.82 | BCHE (0.31) | — | |
| SCHEMBL6156481 | 0.82 | MAOB (0.39) | APPNR4A1NR4A2NR4A3ALOX5 | |
| SCHEMBL6155637 | 0.79 | MAOB (0.40) | APPNR4A1NR4A2NR4A3BCL2 | |
| SCHEMBL6156001 | 0.77 | VDR (0.41) | APPNR4A1NR4A2NR4A3ALOX5 | |
| SCHEMBL6156388 | 0.75 | ALOX5 (0.39) | NR4A1NR4A2NR4A3ALOX5BCL2 | |
| SCHEMBL6155445 | 0.73 | NR4A1 (0.40) | APPNR4A1NR4A2NR4A3ALOX5 | |
| SCHEMBL2785504 | 0.72 | CYSLTR2 (0.40) | ALOX5 | |
| SCHEMBL6155587 | 0.71 | CYSLTR2 (0.44) | APPNR4A1NR4A2NR4A3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | claimed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | claimed |
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |