Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22804104 | 1.00 | SLC7A5 (0.45) | SLC7A5CTSSCTSKESR1ESR2 | |
| SCHEMBL22804055 | 1.00 | SLC7A5 (0.45) | SLC7A5CTSSCTSKESR1ESR2 | |
| SCHEMBL7273450 | 0.90 | SLC7A5 (0.43) | SLC7A5CTSSCTSKESR1ESR2 | |
| SCHEMBL6155226 | 0.88 | CTSS (0.41) | SLC7A5CTSSCTSKESR1ESR2 | |
| SCHEMBL17459537 | 0.85 | TPSAB1 (0.45) | CTSSCTSKITGA4ITGB7 | |
| SCHEMBL4778626 | 0.85 | CTSS (0.44) | SLC7A5CTSSCTSKESR1ESR2 | |
| SCHEMBL8766144 | 0.85 | CTSS (0.44) | SLC7A5CTSSCTSKESR1ESR2 | |
| SCHEMBL6661008 | 0.85 | CTSS (0.44) | SLC7A5CTSSCTSKESR1ESR2 | |
| SCHEMBL7163413 | 0.84 | SLC7A5 (0.58) | SLC7A5ESR1ESR2FOLH1 | |
| SCHEMBL7163410 | 0.84 | SLC7A5 (0.58) | SLC7A5ESR1ESR2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575911-A2 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004046091-A2 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-03 | — | — | WO | disclosed |