Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666295 | 0.83 | KDM4E (0.40) | ALDH1A1KDM4EL3MBTL1HPGDTSHR | |
| SCHEMBL3063888 | 0.81 | ALPL (0.36) | ALDH1A1KDM4EPOLBMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL10669237 | 0.81 | KDM4E (0.39) | ALDH1A1KDM4EL3MBTL1HPGDTSHR | |
| SCHEMBL841237 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBMAPTTDP1 | |
| SCHEMBL6156337 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBMAPTTDP1 | |
| SCHEMBL841632 | 0.75 | GAA (0.51) | ALDH1A1KDM4EPOLBMAPTNR4A2 | |
| SCHEMBL21723868 | 0.74 | KMT2A (0.43) | ALDH1A1KDM4EPOLBL3MBTL1HPGD | |
| SCHEMBL720425 | 0.74 | KLKB1 (0.53) | ALDH1A1POLBMAPTTDP1L3MBTL1 | |
| SCHEMBL21723813 | 0.73 | KMT2A (0.38) | ALDH1A1KDM4EPOLBMAPTTDP1 | |
| SCHEMBL11333507 | 0.72 | HTT (0.35) | ALDH1A1KDM4EMAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580189-A1 | 4-AMINO-5-METHYLPYRAZOLE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Sankyo Agro Company, Limited (JP) | 2005-09-28 | — | — | EP | disclosed |