Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154440 | 0.86 | TSHR (0.42) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL6155749 | 0.82 | ACHE (0.40) | ALDH1A1POLBGAAACHELMNA | |
| SCHEMBL841237 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBGAALMNA | |
| SCHEMBL27634513 | 0.82 | ACHE (0.40) | ALDH1A1KDM4EPOLBGAAACHE | |
| SCHEMBL6971478 | 0.81 | ACHE (0.39) | ALDH1A1POLBACHELMNANAMPT | |
| SCHEMBL6154824 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KDM4EPOLBGAALMNA | |
| SCHEMBL841632 | 0.76 | GAA (0.51) | ALDH1A1KDM4EPOLBGAASMN1; SMN2 | |
| SCHEMBL11079834 | 0.76 | ALDH1A1 (0.37) | ALDH1A1KDM4EPOLBGAALMNA | |
| SCHEMBL841373 | 0.76 | SMN1; SMN2 (0.39) | ALDH1A1KDM4EPOLBGAALMNA | |
| SCHEMBL720425 | 0.75 | KLKB1 (0.53) | ALDH1A1POLBLMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580189-A1 | 4-AMINO-5-METHYLPYRAZOLE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Sankyo Agro Company, Limited (JP) | 2005-09-28 | — | — | EP | disclosed |