Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155762 | 0.92 | CYSLTR2 (0.36) | PTGER3CYSLTR2CYSLTR1MAOBMRGPRX4 | |
| SCHEMBL6155407 | 0.85 | CYSLTR2 (0.49) | PTGER3CYSLTR2CYSLTR1MRGPRX4FFAR1 | |
| SCHEMBL6878849 | 0.84 | CYSLTR2 (0.39) | PTGER3CYSLTR2CYSLTR1MAOBMRGPRX4 | |
| SCHEMBL2106606 | 0.84 | VDR (0.43) | PTGER3CYSLTR2CYSLTR1MAOBMRGPRX4 | |
| SCHEMBL6155133 | 0.80 | CYSLTR2 (0.37) | PTGER3CYSLTR2CYSLTR1FFAR1ALOX5 | |
| SCHEMBL5968372 | 0.78 | PTGER3 (0.41) | PTGER3CYSLTR2CYSLTR1FFAR1BCHE | |
| SCHEMBL2106608 | 0.78 | MRGPRX4 (0.42) | PTGER3MRGPRX4FFAR1ALOX5 | |
| SCHEMBL2785501 | 0.76 | VDR (0.49) | PTGER3CYSLTR2CYSLTR1FFAR1BCHE | |
| SCHEMBL2107787 | 0.76 | VDR (0.40) | PTGER3CYSLTR2CYSLTR1MAOBMRGPRX4 | |
| SCHEMBL6154987 | 0.74 | PTGER3 (0.34) | PTGER3CYSLTR2CYSLTR1MAOBMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |