SCHEMBL2107787

SCHEMBL2107787

CC(CCCC(C)(C)O)c1cccc(COc2ccc(CO)c(CO)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
VDR P11473 3/20 0.40
CYSLTR2 Q9NS75 1/20 0.38
CYSLTR1 Q9Y271 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.37
PTGER3 P43115 1/20 0.36
BCHE P06276 1/20 0.36
MAOB P27338 3/20 0.36
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6155571 0.91 VDR (0.46) VDRCYSLTR2CYSLTR1BCHEFFAR1
SCHEMBL2106606 0.89 VDR (0.43) VDRCYSLTR2CYSLTR1MRGPRX4PTGER3
SCHEMBL6155242 0.89 VDR (0.44) VDRCYSLTR2CYSLTR1BCHEFFAR1
SCHEMBL6155762 0.84 CYSLTR2 (0.36) CYSLTR2CYSLTR1MRGPRX4PTGER3BCHE
SCHEMBL2107789 0.83 MRGPRX4 (0.44) CYSLTR2CYSLTR1MRGPRX4BCHECYP4F2
SCHEMBL2109172 0.83 VDR (0.41) VDRCYSLTR2CYSLTR1BCHEFFAR1
SCHEMBL2785501 0.81 VDR (0.49) VDRCYSLTR2CYSLTR1PTGER3BCHE
SCHEMBL6155609 0.79 VDR (0.48) VDRCYSLTR2CYSLTR1PTGER3BCHE
SCHEMBL2106818 0.79 CYSLTR2 (0.42) CYSLTR2CYSLTR1BCHEFFAR1
SCHEMBL6155503 0.79 VDR (0.47) VDRCYSLTR2CYSLTR1PTGER3FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP claimed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US claimed
EP-1124779-A1 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2001-08-22 EP claimed
WO-2000026167-A1 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2000-05-11 WO claimed
EP-2879656-B2 DYE COMPOSITION IN CREAM FORM COMPRISING AT LEAST ONE OIL AND LITTLE OR NO SOLID FATTY ALCOHOL, DYEING PROCESS AND SUITABLE DEVICE OREAL (FR) 2024-07-17 EP disclosed
US-11730682-B2 Self-standing cosmetic sheet L'OREAL (FR) 2023-08-22 US disclosed
EP-2879649-B2 DYEING COMPOSITION COMPRISING AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE OXIDIZING AGENT AND AT LEAST ONE NON-IONIC, ANIONIC AND AMPHOTERIC SURFACTANT OREAL (FR) 2022-08-24 EP disclosed
EP-2836187-B1 SELF-STANDING COSMETIC SHEET OREAL (FR) 2021-12-08 EP disclosed
CN-112472619-A Dye composition, dyeing method and suitable device 莱雅公司 2021-03-12 CN disclosed
EP-2879656-B1 DYE COMPOSITION IN CREAM FORM COMPRISING AT LEAST ONE OIL AND LITTLE OR NO SOLID FATTY ALCOHOL, DYEING PROCESS AND SUITABLE DEVICE OREAL (FR) 2019-05-29 EP disclosed
US-10226411-B2 Dyeing composition comprising a fatty substance, a non-ionic guar gum, an amphoteric surfactant and a non-ionic or anionic surfactant, and an oxidizing agent, dyeing process and suitable device L'OREAL (FR) 2019-03-12 US disclosed
US-10201483-B2 Dye composition in cream form comprising at least one oil and little or no solid fatty alcohol, dyeing process and suitable device L'OREAL (FR) 2019-02-12 US disclosed
US-20050169945-A1 Composition for protecting keratin material, process of making, uses thereof L'OREAL (FR) 2005-08-04 US disclosed
EP-1559398-A1 Process for preparing a composition for the cosmetic treatment of keratinous materials on the basis of a pressurised fluid and vitamins L'OREAL (FR) 2005-08-03 EP disclosed
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP disclosed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US disclosed
US-20020197289-A1 Compositions and methods for combating the appearance of ageing L'OREAL (FR) 2002-12-26 US disclosed
EP-1262168-A1 Composition containing fibres to combat the skin aging process L'OREAL (FR) 2002-12-04 EP disclosed
EP-1124779-A1 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2001-08-22 EP disclosed
WO-2000026167-A1 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2000-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10226411-B2 Dyeing composition comprising a fatty substance, a non-ionic guar gum, an amphoteric surfactant and a non-ionic or anionic surfactant, and an oxidizing agent, dyeing process and suitable device KRT18, OAT, DSG1 VDR 3553/4885CYSLTR2 2051/4885CYSLTR1 1868/4885
US-20020197289-A1 Compositions and methods for combating the appearance of ageing CYP24A1, CYP27B1, CYP2R1 VDR 4/4885CYSLTR2 4433/4885CYSLTR1 4236/4885
US-10201483-B2 Dye composition in cream form comprising at least one oil and little or no solid fatty alcohol, dyeing process and suitable device KRT18, CUTA, DSG1 VDR 3276/4885CYSLTR2 1935/4885CYSLTR1 1818/4885
US-11730682-B2 Self-standing cosmetic sheet CUTA, DSG1, SUCLG1 VDR 4085/4885CYSLTR2 2427/4885CYSLTR1 2592/4885
US-20050169945-A1 Composition for protecting keratin material, process of making, uses thereof KRT18, PROC, CUTA VDR 514/4885CYSLTR2 3910/4885CYSLTR1 3774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.