Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155935 | 0.87 | IGF1R (0.41) | IGF1RALOX15KLF10VDRADRB2 | |
| SCHEMBL15556080 | 0.87 | VDR (0.45) | VDR | |
| SCHEMBL6154950 | 0.81 | KLF10 (0.45) | IGF1RALOX15KLF10BACE1ADRB2 | |
| SCHEMBL6155280 | 0.80 | KLF10 (0.44) | IGF1RALOX15KLF10BACE1ADRB2 | |
| SCHEMBL21517600 | 0.75 | KAT8 (0.55) | IGF1RALOX15BACE1ADRB3PKM | |
| SCHEMBL14242913 | 0.74 | IGF1R (0.59) | IGF1RALOX15KLF10BACE1ADRB2 | |
| SCHEMBL5635615 | 0.73 | KAT8 (0.58) | IGF1RALOX15BACE1ADRB3 | |
| SCHEMBL30124210 | 0.73 | KAT8 (0.58) | IGF1RALOX15BACE1ADRB3 | |
| SCHEMBL6155530 | 0.73 | HMGCR (0.52) | IGF1RALOX15KLF10VDRADRB2 | |
| SCHEMBL6155538 | 0.73 | HMGCR (0.52) | IGF1RALOX15KLF10VDRADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238011-B1 | THERMOPLASTIC COMPOSITIONS HAVING HIGH DIMENSIONAL STABILITY | ASSOCIATED PACKAGING ENTPR INC (US) | 2005-02-02 | — | — | EP | claimed |
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | claimed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | claimed |
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |