SCHEMBL6155280

SCHEMBL6155280

CC(C)(O)CCCCCc1ccc(CCc2ccc(O)c(CO)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KLF10 Q13118 1/20 0.44
IGF1R P08069 6/20 0.43
ALOX15 P16050 6/20 0.43
ADRB2 P07550 2/20 0.40
ADRB1 P08588 1/20 0.40
PKM P14618 1/20 0.40
BACE1 P56817 1/20 0.39
CDK1 P06493 1/20 0.39
BCHE P06276 1/20 0.38
KAT8 Q9H7Z6 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6154950 0.99 KLF10 (0.45) KLF10IGF1RALOX15ADRB2ADRB1
SCHEMBL6155935 0.93 IGF1R (0.41) KLF10IGF1RALOX15ADRB2ADRB1
SCHEMBL27557366 0.89 BCHE (0.47) IGF1RALOX15BCHE
SCHEMBL6155863 0.85 MMP2 (0.42) KLF10IGF1RALOX15ADRB2ADRB1
SCHEMBL6155861 0.85 MMP2 (0.42) KLF10IGF1RALOX15ADRB2ADRB1
SCHEMBL6155147 0.84 MMP2 (0.43) KLF10IGF1RALOX15ADRB2ADRB1
SCHEMBL6155141 0.84 MMP2 (0.43) KLF10IGF1RALOX15ADRB2ADRB1
SCHEMBL6884197 0.83 ALOX15 (0.63) IGF1RALOX15ADRB2BACE1
SCHEMBL14242913 0.83 IGF1R (0.59) KLF10IGF1RALOX15ADRB2ADRB1
SCHEMBL6155079 0.80 IGF1R (0.39) KLF10IGF1RALOX15ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1282636-C Vitamin D analogues GALDERMA RES & DEV (FR) 2006-11-01 CN claimed
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP claimed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US claimed
CN-1332711-A Vitamin D analogues GALDERMA RES & DEV (FR) 2002-01-23 CN claimed
CN-1282636-C Vitamin D analogues GALDERMA RES & DEV (FR) 2006-11-01 CN disclosed
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP disclosed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US disclosed
CN-1332711-A Vitamin D analogues GALDERMA RES & DEV (FR) 2002-01-23 CN disclosed