Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 12/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10495028 | 0.80 | HTR7 (0.55) | HTR7ALDH1A1TSHRCYP3A4MTNR1A | |
| SCHEMBL14818792 | 0.79 | ALDH1A1 (0.55) | HTR7ALDH1A1TSHRCYP3A4MTNR1A | |
| SCHEMBL8403505 | 0.75 | ALDH1A1 (0.59) | HTR7ALDH1A1TSHRCYP3A4MTNR1A | |
| SCHEMBL29591101 | 0.75 | ALDH1A1 (0.59) | HTR7ALDH1A1TSHRCYP3A4MTNR1A | |
| SCHEMBL2388543 | 0.75 | ALDH1A1 (0.59) | HTR7ALDH1A1TSHRCYP3A4MTNR1A | |
| SCHEMBL5145010 | 0.75 | ALDH1A1 (0.59) | HTR7ALDH1A1TSHRCYP3A4MTNR1A | |
| SCHEMBL20390461 | 0.75 | HTR7 (0.54) | HTR7ALDH1A1TSHRCYP3A4MTNR1A | |
| SCHEMBL4500081 | 0.74 | ALDH1A1 (0.57) | HTR7ALDH1A1TSHRCYP3A4MTNR1A | |
| SCHEMBL29235215 | 0.74 | ALDH1A1 (0.57) | HTR7ALDH1A1TSHRCYP3A4MTNR1A | |
| SCHEMBL6155493 | 0.74 | APP (0.44) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |