Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155416 | 0.87 | HSP90AA1 (0.38) | MTNR1AMTNR1BHSP90AA1HSP90AB1POLQ | |
| SCHEMBL30206480 | 0.77 | RAB9A (0.47) | HSP90AA1HSP90AB1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL31738064 | 0.74 | F2 (0.39) | MTNR1AMTNR1BHSP90AA1HSP90AB1CA12 | |
| SCHEMBL6879525 | 0.70 | MEN1 (0.47) | MAPTMEN1KMT2A | |
| SCHEMBL6879522 | 0.70 | ALDH1A1 (0.45) | MTNR1AMTNR1BKMT2A | |
| SCHEMBL341880 | 0.69 | KMT2A (0.53) | HSP90AA1HSP90AB1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7706827 | 0.69 | CA1 (0.50) | HSP90AA1HSP90AB1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL2676116 | 0.69 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1KMT2ACA12CA1 | |
| SCHEMBL15266769 | 0.68 | ALDH1A1 (0.48) | MTNR1AMTNR1BPOLQMAPTSMN1; SMN2 | |
| SCHEMBL1077335 | 0.68 | CNR2 (0.42) | HSP90AA1HSP90AB1MEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |