Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878730 | 0.90 | FFAR1 (0.40) | FFAR1FFAR4 | |
| SCHEMBL6884926 | 0.86 | FFAR1 (0.34) | FFAR1FFAR4 | |
| SCHEMBL6156487 | 0.80 | CYSLTR2 (0.50) | FFAR1FFAR4RXRANR1H2NR1H3 | |
| SCHEMBL7777946 | 0.79 | FFAR1 (0.35) | FFAR1FFAR4 | |
| SCHEMBL6155420 | 0.77 | ACACB (0.43) | — | |
| SCHEMBL6155454 | 0.73 | MAPT (0.40) | MAPTRXFP1TBXAS1 | |
| SCHEMBL6155458 | 0.73 | MAPT (0.40) | MAPTRXFP1TBXAS1 | |
| SCHEMBL7775456 | 0.71 | FFAR1 (0.44) | FFAR1FFAR4MAPTRXFP1 | |
| SCHEMBL6881362 | 0.71 | BACE1 (0.35) | FFAR1FFAR4RXRA | |
| SCHEMBL6881366 | 0.71 | BACE1 (0.35) | FFAR1FFAR4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |