Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155454 | 0.90 | MAPT (0.40) | CYP4F2CYP4A11HDAC6HDAC1BACE1 | |
| SCHEMBL6155458 | 0.90 | MAPT (0.40) | CYP4F2CYP4A11HDAC6HDAC1BACE1 | |
| SCHEMBL6156155 | 0.83 | HMGCR (0.49) | CYP4F2CYP4A11BACE1HDAC4MEF2D | |
| SCHEMBL13008128 | 0.76 | SIRT2 (0.36) | BACE1HSP90AB1SIRT2KDM4EALDH1A1 | |
| SCHEMBL6878730 | 0.75 | FFAR1 (0.40) | HDAC6HDAC1PDE3BPDE3AP2RY12 | |
| SCHEMBL6878844 | 0.75 | MTNR1A (0.41) | HDAC6HDAC1 | |
| SCHEMBL4841595 | 0.74 | HDAC6 (0.41) | HDAC6HDAC1PDE3BPDE3AP2RY12 | |
| SCHEMBL20298754 | 0.73 | LCK (0.44) | BACE1KDM4EALDH1A1HPGD | |
| SCHEMBL6885108 | 0.73 | CYP4F2 (0.42) | CYP4F2CYP4A11HDAC6HDAC1PDE3B | |
| SCHEMBL6885094 | 0.73 | CYP4F2 (0.42) | CYP4F2CYP4A11HDAC6HDAC1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |