Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.42 |
| ▸ | BCL2 | P10415 | 2/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156203 | 0.97 | MTNR1A (0.42) | MTNR1AMTNR1BBCL2LTB4RLTB4R2 | |
| SCHEMBL6156550 | 0.90 | BCL2 (0.41) | MTNR1AMTNR1BBCL2LTB4RLTB4R2 | |
| SCHEMBL6157281 | 0.88 | MTNR1A (0.39) | MTNR1AMTNR1BBCL2LTB4RLTB4R2 | |
| SCHEMBL6155831 | 0.86 | VDR (0.46) | MTNR1AMTNR1BBCL2APP | |
| SCHEMBL6155485 | 0.83 | VDR (0.45) | MTNR1AMTNR1BBCL2APP | |
| SCHEMBL6156502 | 0.81 | BCL2 (0.44) | MTNR1AMTNR1BBCL2LTB4RLTB4R2 | |
| SCHEMBL6156109 | 0.81 | CFD (0.39) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL6155835 | 0.81 | APP (0.44) | MTNR1AMTNR1BBCL2APPNR4A1 | |
| SCHEMBL6156207 | 0.78 | MTNR1A (0.42) | MTNR1AMTNR1BBCL2LTB4RLTB4R2 | |
| SCHEMBL6156495 | 0.78 | BCHE (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |