Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17460433 | 0.90 | CA2 (0.47) | GAACTSLLMNACA2ALDH1A1 | |
| SCHEMBL6153740 | 0.85 | GAA (0.44) | GAACTSLLMNACA2ALDH1A1 | |
| SCHEMBL18857832 | 0.83 | CA2 (0.44) | GAACTSLLMNACA2ALDH1A1 | |
| SCHEMBL6153593 | 0.82 | ALDH1A1 (0.46) | CA2ALDH1A1CA7POLBKMT2A | |
| SCHEMBL6154154 | 0.82 | ALDH1A1 (0.46) | CA2ALDH1A1CA7POLBKMT2A | |
| SCHEMBL6154318 | 0.82 | ALDH1A1 (0.46) | CA2ALDH1A1CA7POLBKMT2A | |
| SCHEMBL6154419 | 0.81 | ALDH1A1 (0.58) | LMNAALDH1A1POLBPPARGPPARA | |
| SCHEMBL6155171 | 0.80 | CYP1A2 (0.50) | GAACTSLLMNACA2ALDH1A1 | |
| SCHEMBL7925816 | 0.79 | GAA (0.49) | GAACTSLLMNACA2ALDH1A1 | |
| SCHEMBL21378598 | 0.79 | GAA (0.49) | GAACTSLLMNACA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916654-B1 | SULFONIC ESTER DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USE THEREOF | KANEKA CORP (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6410773-B1 | OPTICAL ACTIVE MATERIAL; ENKEPHALINASE INHIBITORS; HYPOTENSIVE AGENTS | KANEKA CORPORATION (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6121477-A | Sulfonic ester derivatives, process for preparing the same, and use thereof | KANEKA CORPORATION (JP) | 2000-09-19 | — | — | US | disclosed |