Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509312 | 0.82 | GPR3 (1.00) | GPR3HRH3SLC22A2SLC22A3KMT2A | |
| Hydrochloric Acid SCHEMBL7195502 | 0.81 | GPR3 (0.41) | GPR3SLC22A2SLC22A3PDK2ALDH1A1 | |
| SCHEMBL28709520 | 0.80 | GPR3 (0.95) | GPR3HRH3SLC22A2SLC22A3KMT2A | |
| SCHEMBL6855217 | 0.80 | GPR3 (0.55) | GPR3SLC22A2SLC22A3ALDH1A1HSD17B10 | |
| SCHEMBL5526151 | 0.79 | PDK2 (0.50) | GPR3HRH3PDK2ALDH1A1TSHR | |
| SCHEMBL28329563 | 0.75 | HDAC3 (0.42) | GPR3PDK2ALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7200396 | 0.73 | ALDH1A1 (0.40) | PDK2ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL14746024 | 0.69 | GPR3 (0.40) | GPR3HRH3SLC22A2SLC22A3ALDH1A1 | |
| SCHEMBL10111159 | 0.69 | GPR3 (0.52) | GPR3HRH3ALDH1A1TSHRHSD17B10 | |
| SCHEMBL6676651 | 0.68 | GPR3 (0.62) | GPR3HRH3SLC22A2SLC22A3PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553985-A2 | BIPHENYLS AND FLUORENES AS IMAGING AGENTS IN ALZHEIMER'S DISEASE | The Trustees of The University of Pennsylvania (US) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004032975-A2 | BIPHENYLS AND FLUORENES AS IMAGING AGENTS IN ALZHEIMER'S DISEASE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2004-04-22 | — | — | WO | disclosed |