Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7195502 | 0.91 | GPR3 (0.41) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| Hydrochloric Acid SCHEMBL7197340 | 0.79 | — | — | |
| SCHEMBL6155884 | 0.73 | GPR3 (0.68) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| Hydrochloric Acid SCHEMBL28058576 | 0.72 | MEN1 (0.40) | ALDH1A1TSHRHSD17B10TERTCYP3A4 | |
| Hydrochloric Acid SCHEMBL7191899 | 0.72 | GPR3 (0.34) | ALDH1A1TSHRCYP3A4MAPK1MAPT | |
| Hydrochloric Acid SCHEMBL3273189 | 0.71 | MAOA (0.37) | ALDH1A1ALOX15HSD17B10CYP3A4TDP1 | |
| SCHEMBL5526151 | 0.69 | PDK2 (0.50) | ALDH1A1TSHRHSD17B10CYP3A4MAPK1 | |
| SCHEMBL5528114 | 0.68 | PGR (0.48) | ALDH1A1TSHRALOX15HSD17B10APP | |
| SCHEMBL12844048 | 0.68 | ALDH1A1 (0.46) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| SCHEMBL13569394 | 0.67 | SNCA (0.43) | ALDH1A1TSHRHSD17B10APPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942006-B1 | Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst | TOSOH CORP (JP) | 2003-06-04 | — | — | EP | disclosed |