Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155936 | 0.85 | VDR (0.48) | FFAR1ALOX5MAOB | |
| SCHEMBL2785504 | 0.81 | CYSLTR2 (0.40) | FFAR1ALOX5KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6155616 | 0.79 | ALOX5 (0.39) | FFAR1ALOX5KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6155510 | 0.78 | MAPK1 (0.39) | FFAR1ALOX5KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6888584 | 0.76 | KMT2A (0.42) | ALOX5KMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL4169952 | 0.75 | APP (0.40) | ALOX5MAOB | |
| SCHEMBL6156388 | 0.75 | ALOX5 (0.39) | ALOX5MAOB | |
| SCHEMBL6158294 | 0.74 | PDK1 (0.41) | KMT2ASMN1; SMN2MEN1MAOBLMNA | |
| SCHEMBL6883442 | 0.74 | BCHE (0.52) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2783957 | 0.74 | MAOB (0.42) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | claimed |
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |