Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 15/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156568 | 0.80 | CA1 (0.64) | — | |
| SCHEMBL6264342 | 0.79 | HPGD (0.49) | SLC6A5 | |
| SCHEMBL6267497 | 0.75 | HPGD (0.51) | SLC6A5NPC1RAB9A | |
| SCHEMBL6157584 | 0.73 | KCNA5 (0.43) | SLC6A5NPC1RAB9A | |
| SCHEMBL6266482 | 0.72 | KMT2A (0.43) | SLC6A5 | |
| SCHEMBL31241193 | 0.70 | ESRRG (0.48) | NPC1RAB9AESRRG | |
| SCHEMBL31241194 | 0.70 | ESRRG (0.48) | NPC1RAB9AESRRG | |
| SCHEMBL6156971 | 0.70 | MAPK8 (0.43) | NPC1RAB9A | |
| SCHEMBL6267859 | 0.69 | HPGD (0.47) | — | |
| SCHEMBL5422657 | 0.68 | TACR1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501813-A2 | BENZOTHIADIAZEPINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Astrazeneca AB (SE) | 2005-02-02 | — | — | EP | claimed |
| WO-2003091232-A2 | BENZOTHIADIAZEPINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 2003-11-06 | — | — | WO | claimed |