Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266482 | 0.80 | KMT2A (0.43) | HPGDL3MBTL1LMNAGAAHTT | |
| SCHEMBL22515531 | 0.79 | HTT (0.56) | HPGDL3MBTL1LMNAGAAHTT | |
| SCHEMBL6156056 | 0.79 | SLC6A5 (0.47) | SLC6A5 | |
| SCHEMBL8894839 | 0.78 | ALDH1A1 (0.62) | LMNAHTTALDH1A1KDM4EMAPT | |
| SCHEMBL6267497 | 0.78 | HPGD (0.51) | HPGDLMNAALDH1A1KDM4ESLC6A5 | |
| SCHEMBL6156971 | 0.78 | MAPK8 (0.43) | HPGDL3MBTL1LMNAGAAHTT | |
| SCHEMBL6267859 | 0.77 | HPGD (0.47) | HPGDGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL6156568 | 0.76 | CA1 (0.64) | LMNAGAAALDH1A1MEN1KMT2A | |
| SCHEMBL6157584 | 0.76 | KCNA5 (0.43) | L3MBTL1SLC6A5MEN1KMT2A | |
| SCHEMBL6158947 | 0.75 | KCNA5 (0.42) | HPGDL3MBTL1LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597245-A1 | BENZOTHIAZEPINE AND BENZOTHIEPINE DERIVATIVES | AstraZeneca AB (SE) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004076430-A1 | BENZOTHIAZEPINE AND BENZOTHIEPINE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-09-10 | — | — | WO | disclosed |