SCHEMBL6156472

SCHEMBL6156472

OCCNc1ccccc1NCCO

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.57
GLA P06280 2/20 0.57
MAPK1 P28482 1/20 0.52
ALDH1A1 P00352 4/20 0.48
GAA P10253 3/20 0.48
MAPT P10636 2/20 0.48
HPGD P15428 2/20 0.48
HSD17B10 Q99714 2/20 0.48
TSHR P16473 1/20 0.48
HTT P42858 1/20 0.48
RECQL P46063 2/20 0.47
POLB P06746 3/20 0.47
RAD52 P43351 2/20 0.47
RAB9A P51151 2/20 0.47
MITF O75030 1/20 0.47
LMNA P02545 1/20 0.47
TTR P02766 1/20 0.47
CYP2C19 P33261 1/20 0.46
MCL1 Q07820 1/20 0.45
TOP2B Q02880 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9567833 0.89 KDM4E (0.53) KDM4EGLAMAPK1ALDH1A1GAA
SCHEMBL2204571 0.85 KDM4E (0.52) KDM4EGLAMAPK1ALDH1A1GAA
SCHEMBL29589735 0.84 MAPT (0.75) KDM4EGLAMAPK1ALDH1A1GAA
SCHEMBL7375160 0.84 KDM4E (0.49) KDM4EGLAMAPK1ALDH1A1GAA
SCHEMBL29903457 0.84 KDM4E (0.49) KDM4EGLAMAPK1ALDH1A1GAA
SCHEMBL18647775 0.84 KDM4E (0.49) KDM4EGLAMAPK1ALDH1A1GAA
SCHEMBL4629056 0.84 RAB9A (0.51) KDM4EGLAMAPK1ALDH1A1GAA
SCHEMBL4452683 0.84 KDM4E (0.49) KDM4EGLAMAPK1ALDH1A1GAA
SCHEMBL5962621 0.84 KDM4E (0.49) KDM4EGLAMAPK1ALDH1A1GAA
SCHEMBL532717 0.84 RAD52 (0.51) KDM4EGLAMAPK1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105853246-B Keratin dyeing compositions and application thereof comprising free radical scavenger and chelating agent 诺赛尔股份有限公司 2019-07-26 CN claimed
EP-1301163-B1 OXIDATIVE HAIR COLOURING AGENTS CONTAINING AT LEAST ONE DISUBSTITUITED 2,4-DIAMINO PHENYL ETHER AS A COUPLING COMPONENT HENKEL KGAA (DE) 2005-01-26 EP claimed
CN-110035739-A Dye composite comprising 12- hydroxy stearic acid, organic amine and dyestuff 欧莱雅 2019-07-19 CN disclosed
CN-108697624-A The oxidising composition for including fatty material and oxygen alkylene surfactant for handling keratin material 莱雅公司 2018-10-23 CN disclosed
US-6051294-A RETORT-STERILIZABLE PACKAGING MATERIALS EXHIBITING HIGH BARRIER TO OXYGEN THE DOW CHEMICAL COMPANY (US) 2000-04-18 US disclosed
US-5814373-A PACKAGING OF OXYGEN SENSITIVE MATERIALS INSIDE A CONTAINER COMPRISING A THERMOPLASTIC POLYMER DOW CHEMICAL COMPANY (US) 1998-09-29 US disclosed