Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | FGB | P02675 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156472 | 0.84 | KDM4E (0.57) | KDM4EGLAMAPK1TOP2BALDH1A1 | |
| SCHEMBL2204571 | 0.76 | KDM4E (0.52) | KDM4EGLAMAPK1TOP2BALDH1A1 | |
| SCHEMBL532717 | 0.74 | RAD52 (0.51) | KDM4EGLAMAPK1ALDH1A1GAA | |
| SCHEMBL30128490 | 0.74 | KDM4E (0.49) | KDM4EGLAMAPK1TOP2BALDH1A1 | |
| SCHEMBL29903457 | 0.74 | KDM4E (0.49) | KDM4EGLAMAPK1TOP2BALDH1A1 | |
| SCHEMBL18647775 | 0.74 | KDM4E (0.49) | KDM4EGLAMAPK1TOP2BALDH1A1 | |
| SCHEMBL4629056 | 0.74 | RAB9A (0.51) | KDM4EGLAMAPK1ALDH1A1GAA | |
| SCHEMBL5962621 | 0.74 | KDM4E (0.49) | KDM4EGLAMAPK1TOP2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL7838711 | 0.74 | KDM4E (0.50) | KDM4EGLAMAPK1ALDH1A1GAA | |
| SCHEMBL7375160 | 0.74 | KDM4E (0.49) | KDM4EGLAMAPK1TOP2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538228-B2 | Oxazoline ligands for asymmetric catalysis | THE PENN STATE RESEARCH FOUNDATION (US) | 2009-05-26 | — | — | US | disclosed |
| WO-2005058917-A2 | NEW OXAZOLINE LIGANDS FOR ASYMMETRIC CATALYSIS | THE PENN STATE RESEARCH FOUNDATION (US) | 2005-06-30 | — | — | WO | disclosed |
| US-20050137403-A1 | New oxazoline ligands for asymmetric catalysis | THE PENN STATE RESEARCH FOUNDATION | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137403-A1 | New oxazoline ligands for asymmetric catalysis | PDXK, WNK1, WNK2 | KDM4E 913/4885GLA 4107/4885MAPK1 2089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.