Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30128490 | 1.00 | KDM4E (0.49) | KDM4EGLAMAPK1MAPTGAA | |
| SCHEMBL30128568 | 0.88 | ALDH1A1 (0.51) | KDM4EMAPTGAAALDH1A1LMNA | |
| SCHEMBL4193150 | 0.88 | ALDH1A1 (0.51) | KDM4EMAPTGAAALDH1A1LMNA | |
| SCHEMBL6201094 | 0.86 | MAPT (0.52) | KDM4EMAPK1MAPTGAAALDH1A1 | |
| SCHEMBL3870595 | 0.86 | KDM4E (0.59) | KDM4EMAPTGAAALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11509573 | 0.86 | ALDH1A1 (0.50) | KDM4EMAPTGAAALDH1A1HDAC3 | |
| Hydrochloric Acid SCHEMBL3871214 | 0.84 | KDM4E (0.57) | KDM4EMAPTGAAALDH1A1LMNA | |
| SCHEMBL6156472 | 0.84 | KDM4E (0.57) | KDM4EGLAMAPK1MAPTGAA | |
| SCHEMBL867417 | 0.82 | PRSS1 (0.47) | KDM4EMAPTGAAALDH1A1LMNA | |
| SCHEMBL215272 | 0.82 | HDAC3 (0.50) | KDM4EMAPTGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104559893-A | Low-temperature epoxy resin adhesive and application thereof | AEROSPACE RES INST MATERIALS & PROC TECHNOLOGY | 2015-04-29 | — | — | CN | claimed |
| EP-0594811-A1 | OXIDATION HAIR DYE BASED ON A CREAMY CARRIER AND PROCESS FOR DYEING HAIR. | WELLA AG (DE) | 1994-05-04 | — | — | EP | claimed |
| WO-1993023006-A1 | OXIDATION HAIR DYE BASED ON A CREAMY CARRIER AND PROCESS FOR DYEING HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 1993-11-25 | — | — | WO | claimed |
| EP-4736882-A2 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | Cullgen (Shanghai), Inc. (CN) | 2026-05-06 | — | — | EP | disclosed |
| EP-3841098-B1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN SHANGHAI INC (CN) | 2026-01-14 | — | — | EP | disclosed |
| US-20250388587-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN SHANGHAI INC (CN) | 2025-12-25 | — | — | US | disclosed |
| US-12410171-B2 | Tropomyosin receptor kinase (TRK) degradation compounds and methods of use | CULLGEN (SHANGHAI), INC. (CN) | 2025-09-09 | — | — | US | disclosed |
| US-12065442-B2 | Tropomyosin receptor kinase (TRK) degradation compounds and methods of use | CULLGEN (SHANGHAI), INC. (CN) | 2024-08-20 | — | — | US | disclosed |
| US-11969472-B2 | Tropomyosin receptor kinase (TRK) degradation compounds and methods of use | CULLGEN (SHANGHAI), INC. (CN) | 2024-04-30 | — | — | US | disclosed |
| CN-115626927-B | Tropomyosin Receptor Kinase (TRK) degrading compounds and methods of use | 上海睿跃生物科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| US-20230257380-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI), INC. (CN) | 2023-08-17 | — | — | US | disclosed |
| US-5288595-A | Treating with fixing bath containing n-oxide compound with mercaptogroup | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0359465-B1 | Novel dyeing system | BRISTOL MYERS CO (US) | 1993-11-18 | — | — | EP | disclosed |
| US-5188927-A | Bleaching | FUJI PHOTO FILM CO., LTD. (JP) | 1993-02-23 | — | — | US | disclosed |
| US-5149700-A | Antiarrhythmic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| WO-1991018904-A1 | SUBSTITUTED ARYLSULFONAMIDES AND BENZAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |
| EP-0359465-A2 | Novel dyeing system | Bristol-Myers Squibb Company (US) | 1990-03-21 | — | — | EP | disclosed |
| US-4327209-A | Process for the production of dibenzazolyl compounds | CIBA-GEIGY CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |
| US-3981677-A | Oxidative hair dye compositions containing N-substituted o-phenylenediamines and method for their use | CLAIROL INCORPORATED (US) | 1976-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257380-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | MUSK, ERBB2, NTRK1 | KDM4E 3125/4885GLA 1658/4885MAPK1 1734/4885 |
| US-11969472-B2 | Tropomyosin receptor kinase (TRK) degradation compounds and methods of use | MUSK, ERBB2, NTRK1 | KDM4E 3125/4885GLA 1658/4885MAPK1 1734/4885 |
| US-12410171-B2 | Tropomyosin receptor kinase (TRK) degradation compounds and methods of use | MUSK, ERBB2, NTRK1 | KDM4E 3125/4885GLA 1658/4885MAPK1 1734/4885 |
| US-20250388587-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | ERBB2, MUSK, ERBB3 | KDM4E 3350/4885GLA 2308/4885MAPK1 908/4885 |
| US-12065442-B2 | Tropomyosin receptor kinase (TRK) degradation compounds and methods of use | MUSK, NTRK1, ERBB2 | KDM4E 3368/4885GLA 1479/4885MAPK1 2479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.