Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655216 | 0.81 | HTR3A (0.43) | SLC18A3ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL4169706 | 0.80 | SLC18A3 (0.42) | SLC18A3MAPT | |
| Hydrochloric Acid SCHEMBL7658988 | 0.79 | KDM1A (0.37) | ALDH1A1ATMMAP1LC3BHTR2AHTR2C | |
| SCHEMBL11540130 | 0.78 | MAPT (0.34) | ALDH1A1LMNAMAPTTP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6997190 | 0.78 | SLC18A3 (0.41) | SLC18A3ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL16571300 | 0.78 | — | — | |
| SCHEMBL3970629 | 0.75 | SLC18A3 (0.43) | SLC18A3ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL1366298 | 0.72 | SLC18A3 (0.38) | SLC18A3ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL9517943 | 0.72 | ACHE (0.42) | SLC18A3ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL1405569 | 0.71 | ESR2 (0.50) | SLC18A3ALDH1A1LMNAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937715-B1 | TETRAHYDROBENZINDOLE COMPOUNDS | MEIJI SEIKA KAISHA (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6355642-B1 | PSYCHOLOGICAL DISORDERS AND BRAIN DISORDERS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-0937715-A1 | TETRAHYDROBENZINDOLE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1999-08-25 | — | — | EP | disclosed |